{"id":"W2950279700","doi":"10.1074/jbc.m117.816272","title":"Elucidation of the 14-3-3ζ interactome reveals critical roles of RNA-splicing factors during adipogenesis","year":2018,"lang":"en","type":"article","venue":"Journal of Biological Chemistry","topic":"14-3-3 protein interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; University of British Columbia; Centre Hospitalier de l’Université de Montréal","funders":"Canadian Institutes of Health Research; Johnson and Johnson","keywords":"Adipogenesis; Interactome; Alternative splicing; RNA splicing; Biology; Cell biology; RNA; Computational biology; Messenger RNA; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002531403,0.0001464223,0.0002785531,0.00002878317,0.0000709716,0.00001113695,0.0003980691,0.000250251,0.0001680415],"category_scores_gemma":[0.002276016,0.00009097595,0.0002924922,0.0001038192,0.0003369653,0.0000108907,0.0001744041,0.0002255517,0.000001129218],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003160362,"about_ca_system_score_gemma":0.00004958314,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000003938974,"about_ca_topic_score_gemma":0.000001565022,"domain_scores_codex":[0.9987262,0.00008081634,0.0006567551,0.0001776212,0.0001828912,0.0001757305],"domain_scores_gemma":[0.9983761,0.00009823935,0.0006085311,0.0002813773,0.000556293,0.00007949529],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001584002,0.00008648856,0.01433896,0.00005172115,0.00007305115,0.000001196411,0.00003882668,0.000006334081,0.9849707,0.000004834059,0.0001039189,0.0001655505],"study_design_scores_gemma":[0.0001971224,0.0002305275,0.03098839,0.0001529851,0.00003235766,0.00008340876,0.0001487118,0.000002639173,0.9676617,0.00007308452,0.000335709,0.00009341562],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986433,0.00029054,0.0002876554,0.0001552615,0.0001841662,0.00005573082,0.00002270081,0.000003542739,0.0003570786],"genre_scores_gemma":[0.9989542,0.00006052512,0.0003569306,0.00003252082,0.0004723466,0.000002259865,0.000005936587,0.00001020797,0.0001051128],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01730906,"threshold_uncertainty_score":0.3709892,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01971642397329957,"score_gpt":0.2942506815718359,"score_spread":0.2745342575985363,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}