{"id":"W2950364755","doi":"10.1002/chin.201132199","title":"ChemInform Abstract: Total Synthesis of Pactamycin.","year":2011,"lang":"en","type":"article","venue":"ChemInform","topic":"Synthesis and Biological Activity","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"","keywords":"Chemistry; Total synthesis; Oxazoline; Yield (engineering); Stereochemistry; Threonine; Combinatorial chemistry; Organic chemistry; Serine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0001620974,0.0001736336,0.00021972,0.00002358208,0.0000338493,0.0000065092,0.0002177258,0.0002414989,0.00114706],"category_scores_gemma":[0.0002900576,0.0001300321,0.0001783604,0.00006015727,0.0001324408,0.000009169441,0.0001169709,0.00007226166,0.00002633487],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001178344,"about_ca_system_score_gemma":0.00003904232,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002999483,"about_ca_topic_score_gemma":0.000002420499,"domain_scores_codex":[0.9991521,1.046669e-7,0.0002798707,0.0002031306,0.0001149166,0.0002499387],"domain_scores_gemma":[0.9993075,0.00003227155,0.0001683172,0.000330166,0.00006517157,0.00009655224],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001522585,0.0001661616,0.0008900556,0.00005080081,0.00006703033,0.00000145015,0.00008029227,1.250962e-8,0.4103273,0.0000615055,0.003513147,0.5846899],"study_design_scores_gemma":[0.0001099349,0.00009574604,0.02805275,0.00001525727,0.00001552713,0.0000136381,0.0001219679,3.546504e-7,0.9627994,0.00002914789,0.008563587,0.0001827274],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"other","genre_gemma":"empirical","genre_scores_codex":[0.391151,0.00004749368,3.002871e-7,0.000009144902,0.00003875322,0.00006352263,0.00002058181,0.00001145789,0.6086578],"genre_scores_gemma":[0.9960446,0.0000643178,0.00008635965,0.00004814131,0.0001014529,0.00002378122,0.00002455317,0.00001089832,0.003595862],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.6050619,"threshold_uncertainty_score":0.9997661,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02096931128952212,"score_gpt":0.2229459162904198,"score_spread":0.2019766050008977,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}