{"id":"W2950368198","doi":"10.3390/mi10060418","title":"Coupling Microfluidic Platforms, Microfabrication, and Tissue Engineered Scaffolds to Investigate Tumor Cells Mechanobiology","year":2019,"lang":"en","type":"review","venue":"Micromachines","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Fonds de Recherche du Québec - Santé; Cancer Research Society","keywords":"Mechanobiology; Microfabrication; Microfluidics; Extracellular matrix; Tumor microenvironment; Nanotechnology; Mechanotransduction; Tissue engineering; Regenerative medicine; 3D cell culture; Materials science; Biology; Cell biology; Cell culture; Biomedical engineering; Tumor cells; Stem cell; Engineering; Pathology; Cancer research; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007721036,0.00147317,0.001211994,0.002807589,0.0002801955,0.001105897,0.001356138,0.001464988,0.002966474],"category_scores_gemma":[0.00058583,0.0004923102,0.0004252428,0.00250395,0.0007570639,0.001772328,0.001084696,0.002101044,0.00282353],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0009690163,"about_ca_system_score_gemma":0.000860735,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009069216,"about_ca_topic_score_gemma":0.001575158,"domain_scores_codex":[0.9997554,0.00002960871,0.00002029596,0.0000551571,0.0001099414,0.00002961054],"domain_scores_gemma":[0.9997576,0.0001121691,0.0000291198,0.00001213294,0.00005973218,0.00002927908],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004935642,0.00009376158,0.0001372472,0.01257491,0.00007355004,0.0002692138,0.0000678306,0.0007664426,0.01012782,0.01849271,0.03271155,0.9246356],"study_design_scores_gemma":[0.000009536333,0.00005188408,0.0003005512,0.001163419,0.00003143917,0.0005712006,0.00002201726,0.0001782391,0.002127285,0.002916476,0.9926084,0.00001954666],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.000119155,0.9959497,0.0007869459,0.0002131847,0.0004330472,0.00001008425,0.00001521825,0.00001735779,0.00245523],"genre_scores_gemma":[0.001006447,0.9947472,0.001030297,0.0002736777,0.0002917963,0.00002200937,0.00004298893,0.000005411459,0.002580015],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002966474,"threshold_uncertainty_score":0.009923816,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02119667963219529,"score_gpt":0.2904689435916328,"score_spread":0.2692722639594375,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}