{"id":"W2950368198","doi":"10.3390/mi10060418","title":"Coupling Microfluidic Platforms, Microfabrication, and Tissue Engineered Scaffolds to Investigate Tumor Cells Mechanobiology","year":2019,"lang":"en","type":"review","venue":"Micromachines","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Fonds de Recherche du Québec - Santé; Cancer Research Society","keywords":"Mechanobiology; Microfabrication; Microfluidics; Extracellular matrix; Tumor microenvironment; Nanotechnology; Mechanotransduction; Tissue engineering; Regenerative medicine; 3D cell culture; Materials science; Biology; Cell biology; Cell culture; Biomedical engineering; Tumor cells; Stem cell; Engineering; Pathology; Cancer research; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001918839,0.0005840898,0.000979777,0.0002438586,0.0001191197,0.00006960108,0.0004095649,0.0004134107,0.00003412316],"category_scores_gemma":[0.00004042928,0.0005133106,0.0002348822,0.0002028164,0.0000394862,0.000005113545,0.0003690207,0.0001792304,0.0002326608],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004034105,"about_ca_system_score_gemma":0.0001707719,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005406312,"about_ca_topic_score_gemma":0.000009392777,"domain_scores_codex":[0.9980761,0.00003118199,0.0005810351,0.0008441384,0.00007127936,0.0003962084],"domain_scores_gemma":[0.998813,0.00003165458,0.0002519061,0.0006292503,0.00008366633,0.0001905225],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.000006293684,0.00002671068,0.000001371614,0.001641077,0.0001480179,0.000003636181,0.00001521486,0.0000022866,0.9697392,0.00005044305,0.01020962,0.01815614],"study_design_scores_gemma":[0.0001179086,0.0001408742,4.762765e-7,0.0006326688,0.0002221246,0.000185316,0.000005461343,0.00001959979,0.2145911,0.00001261035,0.783616,0.0004558718],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.01063044,0.986195,0.0009336284,0.00002996654,0.000838294,0.0009151647,0.0003978304,0.00002982952,0.00002991116],"genre_scores_gemma":[0.0005029122,0.9942301,0.0008352338,0.0002256782,0.0003258382,0.00009324394,0.002166558,0.0001277734,0.001492673],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.7734064,"threshold_uncertainty_score":0.9997318,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02119667963219529,"score_gpt":0.2904689435916328,"score_spread":0.2692722639594375,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}