{"id":"W2950392607","doi":"10.1093/ndt/gfz106.fp633","title":"FP633A DOUBLE-BLIND, RANDOMISED, PLACEBO-CONTROLLED PHASE 2B STUDY TO ASSESS THE EFFECT OF SNF472 ADDED TO STANDARD OF CARE ON PROGRESSION OF CARDIOVASCULAR CALCIFICATION IN PATIENTS WITH END-STAGE RENAL DISEASE ON MAINTENANCE HAEMODIALYSIS (CaLIPSO STUDY)","year":2019,"lang":"en","type":"article","venue":"Nephrology Dialysis Transplantation","topic":"Renal and Vascular Pathologies","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"","keywords":"Medicine; Placebo; End stage renal disease; Disease; Stage (stratigraphy); Internal medicine; Kidney disease; Calcification; Physical therapy; Pathology; Alternative medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001768355,0.0003279557,0.001922058,0.0006120973,0.00005947916,0.000009895357,0.0002035158,0.00008545604,0.00001839607],"category_scores_gemma":[0.0001462962,0.000181775,0.0005719712,0.0007075917,0.00008542969,0.00006778255,0.00001762204,0.0001994569,0.000003716671],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008357543,"about_ca_system_score_gemma":0.0000828363,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001004218,"about_ca_topic_score_gemma":0.0001675528,"domain_scores_codex":[0.9955227,0.001641362,0.0008479435,0.000606092,0.00112349,0.0002583835],"domain_scores_gemma":[0.997695,0.0005709117,0.0003780011,0.0008453307,0.000391873,0.0001189339],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.7695612,0.002019393,0.1708655,0.0002805072,0.002240323,0.00004567319,0.004900428,0.04575073,0.001275411,0.000004022659,0.000001840555,0.003054992],"study_design_scores_gemma":[0.6479327,0.04748674,0.2745763,0.0003792593,0.0088995,8.446247e-7,0.001108259,0.000132916,0.01926125,8.30942e-7,0.000009716514,0.0002116337],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9820313,0.00005814311,0.0008451183,0.00005771361,0.00005043796,0.01675232,0.0001546435,0.00001940142,0.00003091794],"genre_scores_gemma":[0.9980888,0.00002175572,0.00005969249,0.00003171819,0.00002192351,0.001400598,0.0003424552,0.00002456429,0.000008467795],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1216284,"threshold_uncertainty_score":0.7412568,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01740826245271844,"score_gpt":0.3120300023369642,"score_spread":0.2946217398842458,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}