{"id":"W2950426289","doi":"10.1136/annrheumdis-2019-eular.8676","title":"LB0001 EFFICACY AND SAFETY OF FILGOTINIB FOR PATIENTS WITH RHEUMATOID ARTHRITIS WITH INADEQUATE RESPONSE TO METHOTREXATE: FINCH1 PRIMARY OUTCOME RESULTS","year":2019,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Chronic Lymphocytic Leukemia Research","field":"Medicine","cited_by":28,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Toronto; Mount Sinai Hospital","funders":"National Institute for Health and Care Research","keywords":"Medicine; Rheumatoid arthritis; Adalimumab; Internal medicine; Clinical endpoint; Methotrexate; Adverse effect; Placebo; Clinical trial","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001839034,0.0006100141,0.001333546,0.000506597,0.0004242704,0.0009032815,0.0006468281,0.0008286352,0.005655605],"category_scores_gemma":[0.002414656,0.0001643747,0.002345877,0.0005486042,0.0004728042,0.0006491941,0.000360135,0.001485302,0.0007877117],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001802674,"about_ca_system_score_gemma":0.001603049,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.006046052,"about_ca_topic_score_gemma":0.01559883,"domain_scores_codex":[0.9990149,0.0003249408,0.0000702094,0.000129975,0.0002910551,0.0001688549],"domain_scores_gemma":[0.9985071,0.0004884775,0.0004565579,0.00008405448,0.0002441127,0.0002196283],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.5451026,0.00496418,0.117679,0.004259387,0.01286525,0.0002693708,0.0001505995,0.002954833,0.005445037,0.0007695822,0.01880171,0.2867384],"study_design_scores_gemma":[0.1353527,0.09589733,0.7143623,0.001291801,0.02032978,0.0007659281,0.0003054255,0.002918204,0.006588187,0.00131708,0.02063036,0.0002409556],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9341567,0.02696106,0.0005488555,0.002066106,0.0003004783,0.0006780599,0.01249429,0.0001005556,0.02269401],"genre_scores_gemma":[0.9816309,0.003741976,0.0004863592,0.001032674,0.0002773344,0.000273773,0.007861787,0.0000192977,0.004675857],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006046052,"threshold_uncertainty_score":0.01891994,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02661592140213943,"score_gpt":0.3138811237535323,"score_spread":0.2872652023513929,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}