{"id":"W2950494118","doi":"10.1002/chin.201207026","title":"ChemInform Abstract: Intramolecular Aryne—Ene Reaction: Synthetic and Mechanistic Studies.","year":2012,"lang":"en","type":"article","venue":"ChemInform","topic":"Cyclization and Aryne Chemistry","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"","keywords":"Chemistry; Aryne; Ene reaction; Intramolecular force; Combinatorial chemistry; Computational chemistry; Stereochemistry; Medicinal chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003959227,0.0007083754,0.0002839583,0.000342447,0.0003853567,0.0003942152,0.0005196626,0.0005234178,0.01200543],"category_scores_gemma":[0.000249208,0.0001965172,0.0001938084,0.0002613854,0.0003125318,0.0005793985,0.0003861799,0.0008013177,0.002874643],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003824827,"about_ca_system_score_gemma":0.000499096,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007956704,"about_ca_topic_score_gemma":0.0009419044,"domain_scores_codex":[0.9998242,0.00002332743,0.000007674925,0.00004005382,0.00004838962,0.00005637096],"domain_scores_gemma":[0.9999363,0.0000154476,0.00001386006,0.000009310367,0.00001191691,0.00001318038],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001923144,0.0006128276,0.0004487191,0.0008519075,0.00009357333,0.0008246957,0.000189395,0.00190098,0.9276904,0.01181601,0.006187699,0.04746063],"study_design_scores_gemma":[0.0001654471,0.001191939,0.001310416,0.0000270851,0.00006548456,0.0008395412,0.00002931193,0.001385784,0.9637026,0.000415372,0.03083176,0.00003520144],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7252755,0.01195476,0.03635803,0.0008768696,0.0005352776,0.0005942486,0.00294089,0.001103057,0.2203614],"genre_scores_gemma":[0.9617714,0.004538281,0.007453904,0.0001845482,0.00006803466,0.00008671181,0.001656072,0.0000870927,0.02415388],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01200543,"threshold_uncertainty_score":0.04016215,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01850371669953491,"score_gpt":0.2552719408192904,"score_spread":0.2367682241197555,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}