{"id":"W2950572195","doi":"10.1136/annrheumdis-2019-eular.230","title":"THU0250 EARLY IMPROVEMENT IN SLEDAI-2K RESPONDER INDEX-50 PREDICTS SRI-4 RESPONSE IN A RANDOMIZED PLACEBO-CONTROLLED TRIAL OF USTEKINUMAB (UST) IN SYSTEMIC LUPUS ERYTHEMATOSUS","year":2019,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Chronic Lymphocytic Leukemia Research","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"Krembil Foundation","funders":"","keywords":"Ustekinumab; Medicine; Internal medicine; Placebo; Randomized controlled trial; Gastroenterology; Immunology; Disease; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaresearch","metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.007546444,0.0004017079,0.003265144,0.001102528,0.00002608932,0.00003055081,0.0006433807,0.0002196531,0.0001340726],"category_scores_gemma":[0.01336133,0.0002593825,0.000763164,0.0008617076,0.0003087987,0.0001796425,0.0003081893,0.0003576014,0.00002265579],"about_ca_system_candidate":true,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001978694,"about_ca_system_score_gemma":0.006887021,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001499739,"about_ca_topic_score_gemma":0.00009765248,"domain_scores_codex":[0.9915496,0.002845823,0.002705649,0.0005129121,0.001639421,0.0007466026],"domain_scores_gemma":[0.9891836,0.008011132,0.0009492847,0.001426721,0.0002201628,0.0002090843],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9862859,0.001474072,0.004213753,0.002402443,0.0004634382,0.00005707177,0.003188035,0.0009069605,0.0003447348,0.00009324563,0.000144541,0.000425761],"study_design_scores_gemma":[0.9659654,0.001200542,0.004778082,0.00949903,0.0001679776,0.00005697918,0.001368044,0.01576727,0.0003627215,0.0006208185,0.000003042573,0.0002100499],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.980549,0.001967611,0.000005473189,0.0005575709,0.0003807061,0.01616014,0.00003077698,0.00002468902,0.0003240482],"genre_scores_gemma":[0.9969325,0.0003286014,0.00001208223,0.00008856038,0.00002484322,0.001318377,0.000005610113,0.00004554643,0.00124385],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0203205,"threshold_uncertainty_score":0.9999858,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01873329621188867,"score_gpt":0.3015788661395422,"score_spread":0.2828455699276535,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}