{"id":"W2950572195","doi":"10.1136/annrheumdis-2019-eular.230","title":"THU0250 EARLY IMPROVEMENT IN SLEDAI-2K RESPONDER INDEX-50 PREDICTS SRI-4 RESPONSE IN A RANDOMIZED PLACEBO-CONTROLLED TRIAL OF USTEKINUMAB (UST) IN SYSTEMIC LUPUS ERYTHEMATOSUS","year":2019,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Chronic Lymphocytic Leukemia Research","field":"Medicine","cited_by":2,"is_retracted":false,"has_abstract":false,"ca_institutions":"Krembil Foundation","funders":"","keywords":"Ustekinumab; Medicine; Internal medicine; Placebo; Randomized controlled trial; Gastroenterology; Immunology; Disease; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002062846,0.001894849,0.004247286,0.0005349807,0.000599435,0.001391658,0.001080989,0.002194782,0.006198143],"category_scores_gemma":[0.001715416,0.0009599376,0.002015504,0.0004488157,0.001973527,0.001400409,0.0004784441,0.004225462,0.001102606],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006828408,"about_ca_system_score_gemma":0.0008242151,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000802165,"about_ca_topic_score_gemma":0.001948795,"domain_scores_codex":[0.9989348,0.0005885775,0.00006686534,0.0001624232,0.00006366994,0.0001835951],"domain_scores_gemma":[0.9990273,0.0003145685,0.0001778351,0.00009081613,0.00005662306,0.00033301],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9859958,0.003841234,0.0005862726,0.000253836,0.0006526509,0.00002797048,0.0000305759,0.0001470503,0.001606848,0.00005983806,0.0002434275,0.006554384],"study_design_scores_gemma":[0.9086167,0.08625298,0.003098728,0.00002783195,0.0006511533,0.00003299719,0.00003131252,0.0004121955,0.0004761591,0.00009102401,0.0002864223,0.00002243298],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9925477,0.003532122,0.0003013749,0.0004231456,0.0005975133,0.0008523859,0.0003297772,0.00009787393,0.001318083],"genre_scores_gemma":[0.9948755,0.00118252,0.0005093309,0.0004757369,0.0004505905,0.0008084466,0.0003636841,0.00001448053,0.001319784],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006198143,"threshold_uncertainty_score":0.02073485,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01873329621188867,"score_gpt":0.3015788661395422,"score_spread":0.2828455699276535,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}