{"id":"W2950575276","doi":"10.1021/ol035600s","title":"Total Synthesis of (+)-Cystothiazole A","year":2003,"lang":"en","type":"article","venue":"Organic Letters","topic":"Carbohydrate Chemistry and Synthesis","field":"Chemistry","cited_by":52,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"","keywords":"Chemistry; Aldol reaction; Wittig reaction; Electrophile; Phosphonium salt; Total synthesis; Yield (engineering); Aldehyde; Amide; Thiazole; Catalysis; Stereochemistry; Phosphonium; Combinatorial chemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001122609,0.0004761313,0.0003215089,0.0003213207,0.0003782526,0.0003122908,0.0004819528,0.0002559715,0.00494307],"category_scores_gemma":[0.0001201314,0.0001955969,0.0002586088,0.0005164593,0.0001406206,0.0002521701,0.0004076943,0.0005007266,0.002156284],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003943455,"about_ca_system_score_gemma":0.0008386832,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001904993,"about_ca_topic_score_gemma":0.003117556,"domain_scores_codex":[0.9998759,0.000007853785,0.00001039075,0.00003015025,0.00003758728,0.00003819798],"domain_scores_gemma":[0.9999346,0.00000435486,0.000007564355,0.0000114776,0.00002007087,0.00002209409],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001311137,0.0000532164,0.0001077666,0.0002331562,0.00003221714,0.0003040837,0.00004749792,0.0004286868,0.9763925,0.001399336,0.001104823,0.01976562],"study_design_scores_gemma":[0.00006109702,0.0005347334,0.001080471,0.00001744376,0.00006867127,0.0008392413,0.0000239784,0.0007546018,0.9507334,0.0003309633,0.04553067,0.00002470862],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7566286,0.006694684,0.1243469,0.0004662504,0.0006393839,0.0009940648,0.01188125,0.002790523,0.09555823],"genre_scores_gemma":[0.9296131,0.004381942,0.03504874,0.000123687,0.00004188879,0.0001824797,0.003963389,0.0001895589,0.02645529],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00494307,"threshold_uncertainty_score":0.01653624,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006162883909153663,"score_gpt":0.1816083339812528,"score_spread":0.1754454500720991,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}