{"id":"W2950575276","doi":"10.1021/ol035600s","title":"Total Synthesis of (+)-Cystothiazole A","year":2003,"lang":"en","type":"article","venue":"Organic Letters","topic":"Carbohydrate Chemistry and Synthesis","field":"Chemistry","cited_by":52,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"","keywords":"Chemistry; Aldol reaction; Wittig reaction; Electrophile; Phosphonium salt; Total synthesis; Yield (engineering); Aldehyde; Amide; Thiazole; Catalysis; Stereochemistry; Phosphonium; Combinatorial chemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.00009275124,0.0001479368,0.0002201937,0.00002479172,0.00004467013,0.00001424495,0.000150274,0.00009268299,0.008612221],"category_scores_gemma":[0.0003271236,0.0001496544,0.0001203481,0.0001295916,0.00007359502,0.0000499904,0.00002155197,0.0001156521,0.00006548419],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006239883,"about_ca_system_score_gemma":0.00003839453,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009353344,"about_ca_topic_score_gemma":7.876035e-7,"domain_scores_codex":[0.9991357,0.00001749795,0.0002274006,0.0002212216,0.0001718414,0.0002263124],"domain_scores_gemma":[0.9992527,0.0001692642,0.00009243024,0.0003952933,0.00001907592,0.00007122329],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000007169121,0.00004227968,0.0003386008,0.00009665815,0.00004794822,0.00001492017,0.0001007753,0.000002979847,0.9981792,0.00007068222,0.0008671459,0.0002316407],"study_design_scores_gemma":[0.0001420771,0.000001647257,0.00002976146,0.00003609592,0.00004295162,0.00004828488,0.0001495406,0.000005533803,0.9982991,0.00001649043,0.001062573,0.0001659008],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9729819,0.00004466329,0.00003385241,0.0004179684,0.00005430047,0.000017474,0.00001348524,0.00005294306,0.02638342],"genre_scores_gemma":[0.9991963,0.000005600714,0.000156656,0.0001631531,0.00005814957,0.000009267949,0.000002505883,0.00002937476,0.0003790147],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.02621439,"threshold_uncertainty_score":0.992294,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006162883909153663,"score_gpt":0.1816083339812528,"score_spread":0.1754454500720991,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}