{"id":"W2950620394","doi":"10.1097/01.hs9.0000561796.30124.a4","title":"S879 RESULTS OF ASTRAL‐1 STUDY, A PHASE 3 RANDOMIZED TRIAL OF GUADECITABINE (G) VS TREATMENT CHOICE (TC) IN TREATMENT NAÏVE ACUTE MYELOID LEUKEMIA (TN‐AML) NOT ELIGIBLE FOR INTENSIVE CHEMOTHERAPY (IC)","year":2019,"lang":"en","type":"article","venue":"HemaSphere","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":10,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of Alberta Hospital; Alberta Hospital Edmonton","funders":"","keywords":"Medicine; Decitabine; Internal medicine; Clinical endpoint; Cytarabine; Randomized controlled trial; Regimen; Induction chemotherapy; Oncology; Gastroenterology; Chemotherapy; Surgery","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002077206,0.001294037,0.001736628,0.0003251756,0.0003345489,0.0008929562,0.0006341451,0.001439989,0.009629204],"category_scores_gemma":[0.002213608,0.0004254231,0.002196064,0.0003374406,0.0009000538,0.0008110308,0.0003684365,0.003772267,0.001265602],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006361149,"about_ca_system_score_gemma":0.001011695,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004857139,"about_ca_topic_score_gemma":0.001857528,"domain_scores_codex":[0.9991028,0.0006274724,0.0000442479,0.0001036221,0.00005427843,0.00006752045],"domain_scores_gemma":[0.998921,0.0003531549,0.0002790333,0.00007689342,0.00007055431,0.0002993876],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9688325,0.00579984,0.0009968242,0.0006126182,0.001283235,0.00005349966,0.00006202088,0.0006006304,0.003566838,0.0002730132,0.003601247,0.01431783],"study_design_scores_gemma":[0.9138167,0.07791048,0.002538675,0.00006378719,0.001585833,0.00005562132,0.00003420951,0.0006354008,0.0006367973,0.0004625914,0.002240069,0.00001973163],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9722545,0.005431341,0.0008444068,0.002615678,0.0007890494,0.005949481,0.004753279,0.0001424104,0.007219819],"genre_scores_gemma":[0.9730958,0.002580498,0.002648714,0.003863403,0.0005550439,0.006883767,0.004612796,0.00007551897,0.005684505],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009629204,"threshold_uncertainty_score":0.03221285,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03473661491423022,"score_gpt":0.3619602162914029,"score_spread":0.3272236013771727,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}