{"id":"W2950667956","doi":"10.1016/j.tetlet.2003.09.190","title":"A sequential Claisen/ring-closing metathesis approach to the synthesis of spirocyclic cyclopentanes and cyclohexanes","year":2003,"lang":"en","type":"article","venue":"Tetrahedron Letters","topic":"Synthetic Organic Chemistry Methods","field":"Chemistry","cited_by":21,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Ottawa","funders":"Ontario Innovation Trust","keywords":"Cyclopentanes; Cyclohexanes; Chemistry; Ring-closing metathesis; Metathesis; Closing (real estate); Tricyclohexylphosphine; Claisen rearrangement; Stereochemistry; Cucurbituril; Organic chemistry; Catalysis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0006831503,0.0003759563,0.0005104463,0.00007882134,0.0001647212,0.00007330345,0.0004942326,0.0001352723,0.0005572987],"category_scores_gemma":[0.0008488744,0.0003023382,0.0001753659,0.0002714483,0.0002620587,0.00008139485,0.0001056572,0.0002505124,0.00001645373],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001118225,"about_ca_system_score_gemma":0.00002743639,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007011637,"about_ca_topic_score_gemma":0.000003256127,"domain_scores_codex":[0.9977853,0.0001679316,0.00050173,0.0006185484,0.0004396357,0.0004867955],"domain_scores_gemma":[0.9979926,0.0007943566,0.0001975979,0.0008183086,0.00002562078,0.0001715103],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002384792,0.00009641112,0.001113502,0.0002830238,0.000155951,0.00001144204,0.000502344,0.00006674249,0.9931056,0.0001430047,0.0002912159,0.004206875],"study_design_scores_gemma":[0.0002526872,0.000005907812,0.0003589341,0.0000838989,0.000261707,0.0002945548,0.0006908912,0.00006480375,0.9878995,0.00003619711,0.009681416,0.0003694772],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9770422,0.0002395529,0.001385896,0.001203155,0.00009990426,0.0001649292,0.00001732056,0.00008857778,0.01975845],"genre_scores_gemma":[0.9811931,0.00001993613,0.01788333,0.0004003892,0.000142602,0.00005971821,0.000002414943,0.00006858751,0.000229927],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01952853,"threshold_uncertainty_score":0.9999429,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02158364789057773,"score_gpt":0.2526545383502406,"score_spread":0.2310708904596629,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}