{"id":"W2950694622","doi":"10.1101/672212","title":"Multiple conformations facilitate PilT function in the type IV pilus","year":2019,"lang":"en","type":"preprint","venue":"bioRxiv (Cold Spring Harbor Laboratory)","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":2,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; McMaster University; University of Toronto","funders":"Canada Research Chairs; Canadian Institutes of Health Research; Hospital for Sick Children; Government of Ontario","keywords":"Pilin; Pilus; Chemistry; Crystallography; ATPase; Biophysics; Virulence; Biology; Biochemistry; Enzyme; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001331442,0.0002166395,0.0001599862,0.0001872483,0.0001684849,0.0003619845,0.0001385122,0.0002577259,0.001109125],"category_scores_gemma":[0.0002180122,0.00009308041,0.0001883147,0.0001457004,0.0002482599,0.0002019501,0.0001789104,0.0002875227,0.0003046609],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002085957,"about_ca_system_score_gemma":0.0001280116,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003752312,"about_ca_topic_score_gemma":0.0003894976,"domain_scores_codex":[0.9999331,0.00001263987,0.000005653278,0.00001378198,0.00001616695,0.00001867829],"domain_scores_gemma":[0.9998902,0.0000287388,0.00003222553,0.00001564339,0.00001075329,0.00002250146],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001911505,0.00001219572,0.002494276,0.00002513224,0.000004598943,0.0001564412,0.00002427223,0.0005725361,0.9946864,0.0003828489,0.0000811826,0.001368918],"study_design_scores_gemma":[0.00002208757,0.0001454363,0.0320781,0.0000111045,0.00001084861,0.0006570842,0.0001028822,0.006642948,0.9579057,0.0008274413,0.001582409,0.00001404779],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977781,0.0001988611,0.00141839,0.00004318028,0.000007728601,0.000003363097,0.00009670583,0.00003814112,0.0004154426],"genre_scores_gemma":[0.9989064,0.00003919028,0.0006727151,0.00001133166,0.000001631614,0.000001892753,0.0001188833,0.000007522639,0.000240466],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001109125,"threshold_uncertainty_score":0.003710389,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01966871417256494,"score_gpt":0.2155355301142399,"score_spread":0.1958668159416749,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}