{"id":"W2950773020","doi":"10.1097/01.hs9.0000562404.53930.45","title":"PS1027 ASSESSMENT OF MOLECULAR MRD KINETICS BY ERROR‐CORRECTED NEXT‐GENERATION SEQUENCING PROVIDES INDEPENDENT PROGNOSTIC INFORMATION IN ADULT AML PATIENTS","year":2019,"lang":"en","type":"article","venue":"HemaSphere","topic":"Sarcoma Diagnosis and Treatment","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Cancer Research; Ontario Institute for Cancer Research; University of Alberta; Princess Margaret Cancer Centre","funders":"","keywords":"Medicine; Oncology; Internal medicine; Minimal residual disease; Induction chemotherapy; Chemotherapy; Proportional hazards model; Stage (stratigraphy); Point mutation; DNA sequencing; Gene; Mutation; Leukemia; Biology; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00006876054,0.0001748748,0.0002832928,0.00007445947,0.00001763357,0.00002922257,0.00005493233,0.0001089177,0.0001343985],"category_scores_gemma":[0.0001095278,0.0001506216,0.00006150365,0.0002048808,0.00001491899,0.000267986,0.00003317746,0.0001290154,0.00002590921],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003878888,"about_ca_system_score_gemma":0.0001392443,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002491142,"about_ca_topic_score_gemma":0.00008846869,"domain_scores_codex":[0.9985877,0.00004870172,0.0004960543,0.0001937306,0.0004720281,0.000201764],"domain_scores_gemma":[0.9991179,0.00003935468,0.0002224791,0.0002400982,0.0003071026,0.00007304311],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00003108426,0.0008576263,0.9390155,0.000276382,0.0000538984,0.00001148382,0.0003437443,0.0005629149,0.04720643,0.00009244333,0.0003406197,0.01120788],"study_design_scores_gemma":[0.007884211,0.001877936,0.8012772,0.001178581,0.0002144094,0.00001414331,0.001163708,0.04395952,0.141755,0.00002618591,0.0002597185,0.0003894409],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969016,0.0001717998,0.0001962906,0.00009633446,0.0001350962,0.001571726,0.00001415836,0.00002977394,0.0008832277],"genre_scores_gemma":[0.9969391,0.00002771978,0.001950415,0.0002484303,0.00001442518,0.0001563954,0.0006155435,0.00001763639,0.00003032426],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1377383,"threshold_uncertainty_score":0.6142172,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01952076263891619,"score_gpt":0.2638523238932328,"score_spread":0.2443315612543166,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}