{"id":"W2950785108","doi":"10.1002/chin.200335113","title":"Syntheses of 4‐(3,5‐Bisphenylmethylene‐4‐oxo‐piperidin‐1‐yl)‐4‐oxo‐but‐2Z‐enoic Acid Arylamides as Candidate Cytotoxic Agents.","year":2003,"lang":"en","type":"article","venue":"ChemInform","topic":"Synthesis and biological activity","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Chemistry; Cytotoxic T cell; Combinatorial chemistry; Stereochemistry; Biochemistry; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.000522394,0.0005165282,0.0007535609,0.00006597584,0.0002263199,0.00006164052,0.0005892475,0.0004477267,0.0105902],"category_scores_gemma":[0.002957975,0.0003952266,0.0003855522,0.0002337665,0.0003364714,0.0002602618,0.0001566389,0.0004572545,0.0001943364],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001740493,"about_ca_system_score_gemma":0.0001372208,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001458324,"about_ca_topic_score_gemma":0.00001369781,"domain_scores_codex":[0.9975913,0.000008906676,0.0006787607,0.0005507353,0.0004444531,0.0007258424],"domain_scores_gemma":[0.9977006,0.0007161133,0.000413501,0.0007830431,0.0001093371,0.0002773525],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001201077,0.0002892884,0.001886394,0.0002982185,0.0001576757,0.000019924,0.0002439912,5.941714e-7,0.9403374,0.0003086345,0.001015814,0.05532199],"study_design_scores_gemma":[0.0003099295,0.00007117529,0.0003213316,0.0001484058,0.00006078359,0.00004392816,0.000922816,0.000005244075,0.9660109,0.0004027826,0.03119643,0.000506314],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.6272497,0.0003091053,0.00000133505,0.00003489605,0.00005991047,0.00009202282,0.00007509416,0.00009953625,0.3720784],"genre_scores_gemma":[0.9900035,0.0003259254,0.0001839238,0.0001556625,0.000114036,0.00007277814,0.00003849659,0.00004109738,0.009064639],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3630137,"threshold_uncertainty_score":0.99985,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02630655594605614,"score_gpt":0.2480358257968407,"score_spread":0.2217292698507846,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}