{"id":"W2950785108","doi":"10.1002/chin.200335113","title":"Syntheses of 4‐(3,5‐Bisphenylmethylene‐4‐oxo‐piperidin‐1‐yl)‐4‐oxo‐but‐2Z‐enoic Acid Arylamides as Candidate Cytotoxic Agents.","year":2003,"lang":"en","type":"article","venue":"ChemInform","topic":"Synthesis and biological activity","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Chemistry; Cytotoxic T cell; Combinatorial chemistry; Stereochemistry; Biochemistry; In vitro","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003044446,0.0006227209,0.0002871058,0.0002894726,0.0002346062,0.0002236962,0.0004346471,0.0002537211,0.003301963],"category_scores_gemma":[0.0002503755,0.0002422855,0.0001763919,0.0002526158,0.0001723305,0.0003391294,0.0002844222,0.0004658195,0.001588437],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002934822,"about_ca_system_score_gemma":0.0006594135,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000405327,"about_ca_topic_score_gemma":0.001406329,"domain_scores_codex":[0.9998853,0.00002321026,0.00001316543,0.00001757552,0.00002511754,0.00003567251],"domain_scores_gemma":[0.9999111,0.00001318673,0.00002227839,0.00001140802,0.00001705004,0.00002499732],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003500126,0.00017691,0.000127637,0.0005121692,0.00002498241,0.0006448446,0.0001420314,0.001386686,0.9642843,0.003006836,0.000846057,0.02849754],"study_design_scores_gemma":[0.0001428656,0.001092659,0.0007054043,0.00004316384,0.00003707863,0.0004455365,0.00003370045,0.0006518376,0.9680039,0.0003645631,0.02845908,0.00002020627],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7664093,0.03018242,0.1196561,0.0007187783,0.0007855832,0.001476147,0.003140723,0.0009045919,0.07672632],"genre_scores_gemma":[0.9108056,0.02237821,0.03953411,0.0001889266,0.0001107903,0.0005878989,0.00160143,0.00009793925,0.02469518],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003301963,"threshold_uncertainty_score":0.01104611,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02630655594605614,"score_gpt":0.2480358257968407,"score_spread":0.2217292698507846,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}