{"id":"W2950831804","doi":"10.1021/ja003085c","title":"Remarkable Synthesis of 2-(<i>Z</i>)-6-(<i>E</i>)-4<i>H</i>-[1,4]-Thiazepin-5-ones by Zwitterionic Rhodium-Catalyzed Chemo- and Regioselective Cyclohydrocarbonylative Ring Expansion of Acetylenic Thiazoles","year":2001,"lang":"en","type":"article","venue":"Journal of the American Chemical Society","topic":"Cyclopropane Reaction Mechanisms","field":"Chemistry","cited_by":51,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Ottawa","funders":"","keywords":"Chemistry; Regioselectivity; Alkyl; Rhodium; Ring (chemistry); Aryl; Thiazole; Catalysis; Medicinal chemistry; Ether; Halide; Vinyl ether; Stereochemistry; Organic chemistry; Copolymer","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00007180615,0.0003268493,0.0001432422,0.00010919,0.00009959877,0.0001548171,0.0002922297,0.0001582784,0.001206983],"category_scores_gemma":[0.00009676939,0.0001314111,0.0001435336,0.0001002031,0.0001314493,0.0002078835,0.0001979068,0.000277192,0.0005107392],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001874799,"about_ca_system_score_gemma":0.0001905643,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003721324,"about_ca_topic_score_gemma":0.0009192979,"domain_scores_codex":[0.9999459,0.000006928175,0.00000433631,0.00001320532,0.00001209183,0.00001768645],"domain_scores_gemma":[0.9999627,0.000004151612,0.00001444338,0.000005344087,0.000005373708,0.000007984672],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007246724,0.00001533335,0.00008993579,0.00006402413,0.000006094883,0.0001294683,0.00002997821,0.0003643774,0.9932058,0.00063445,0.0000967154,0.005291348],"study_design_scores_gemma":[0.00002229316,0.000228454,0.0007651593,0.000003396359,0.00001031786,0.000208933,0.000009401531,0.0005427559,0.9940103,0.00007500062,0.004116057,0.000007936371],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9668645,0.002425748,0.01490546,0.0001029382,0.0000533315,0.0000894164,0.0004330355,0.0002442592,0.01488133],"genre_scores_gemma":[0.9876017,0.001332285,0.006461049,0.00003375427,0.00001444436,0.00004612411,0.0003197947,0.00003496971,0.004155829],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001206983,"threshold_uncertainty_score":0.004037797,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006409664775458448,"score_gpt":0.221400720094224,"score_spread":0.2149910553187655,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}