{"id":"W2950843447","doi":"10.1007/s40265-019-01152-7","title":"Damoctocog Alfa Pegol: A Review in Haemophilia A","year":2019,"lang":"en","type":"review","venue":"Drugs","topic":"Hemophilia Treatment and Research","field":"Medicine","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Medicine; Haemophilia; Certolizumab pegol; Haemophilia A; Interim analysis; Haemophilia B; Dosing; Internal medicine; Surgery; Clinical trial; Adalimumab","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006309274,0.0006697563,0.000971192,0.001906089,0.0002521622,0.001010212,0.0007679892,0.0009790773,0.003523102],"category_scores_gemma":[0.0009162164,0.0002294498,0.0008102236,0.00204105,0.0002971378,0.001023156,0.0004721948,0.001327856,0.001219491],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004303889,"about_ca_system_score_gemma":0.0009728359,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001106332,"about_ca_topic_score_gemma":0.001976061,"domain_scores_codex":[0.9997429,0.00006889628,0.00005181885,0.00004676093,0.00006850227,0.00002100148],"domain_scores_gemma":[0.999466,0.000261506,0.0001056798,0.00001159606,0.0001071549,0.00004813648],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0002213981,0.00007726652,0.0002377231,0.03819753,0.0001703984,0.0001992729,0.00006673984,0.0001716177,0.001141175,0.001652706,0.03627606,0.9215881],"study_design_scores_gemma":[0.00006319817,0.0002286169,0.001542615,0.01249325,0.0004397772,0.001414216,0.00005345339,0.00007070148,0.0002548402,0.0006846519,0.9827387,0.00001602186],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001231832,0.9990934,0.00004481634,0.0001436201,0.0001397701,0.000005647227,0.00001510619,0.000003980245,0.0004305281],"genre_scores_gemma":[0.001116773,0.9978426,0.0001544207,0.0003184933,0.0001750665,0.000009725429,0.00004285609,0.000001789109,0.0003382442],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.003523102,"threshold_uncertainty_score":0.01178598,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1245488399548599,"score_gpt":0.4426825854407154,"score_spread":0.3181337454858555,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}