{"id":"W2950848226","doi":"10.1080/23723556.2019.1620051","title":"Tafazzin modulates cellular phospholipid composition to regulate AML stemness","year":2019,"lang":"en","type":"article","venue":"Molecular & Cellular Oncology","topic":"ATP Synthase and ATPases Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; University Health Network","funders":"","keywords":"Cardiolipin; Phospholipid; Cell biology; Myeloid leukemia; Biology; Mitochondrion; Intracellular; Biochemistry; Cancer research; Membrane","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004802937,0.000444455,0.0005500086,0.0001806994,0.0001527711,0.00006552589,0.0006502048,0.0005484145,0.0004513822],"category_scores_gemma":[0.00004021512,0.000464703,0.0003089586,0.0003447442,0.0001393794,0.00001191715,0.0005513488,0.0003128205,0.001124833],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001333793,"about_ca_system_score_gemma":0.0002146493,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008150376,"about_ca_topic_score_gemma":0.000009430517,"domain_scores_codex":[0.9966118,0.0004173073,0.0004998472,0.001101956,0.0004588538,0.0009102265],"domain_scores_gemma":[0.9980056,0.00003127259,0.0001519154,0.001176171,0.0002292672,0.0004057277],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003502511,0.0002578767,0.0005414672,0.00005496585,0.0001397485,0.0002773423,0.00006401733,0.001804214,0.9923086,0.00031433,0.001289625,0.002597626],"study_design_scores_gemma":[0.001126712,0.001130517,0.0001543516,0.00002964117,0.00004131487,0.00002100928,0.00007372408,0.0005571469,0.8687912,0.00009094473,0.1274852,0.0004982412],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.97088,0.001277831,0.02148936,0.0007272311,0.0005080691,0.001036826,0.00003231449,0.00005452826,0.003993876],"genre_scores_gemma":[0.9922146,0.00005456174,0.002123371,0.001331883,0.0002784977,0.00009971324,0.0006908459,0.000117833,0.003088714],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1261955,"threshold_uncertainty_score":0.9997805,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008376650906733405,"score_gpt":0.2720719263811968,"score_spread":0.2636952754744634,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}