{"id":"W2950848226","doi":"10.1080/23723556.2019.1620051","title":"Tafazzin modulates cellular phospholipid composition to regulate AML stemness","year":2019,"lang":"en","type":"article","venue":"Molecular & Cellular Oncology","topic":"ATP Synthase and ATPases Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":3,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto; University Health Network","funders":"","keywords":"Cardiolipin; Phospholipid; Cell biology; Myeloid leukemia; Biology; Mitochondrion; Intracellular; Biochemistry; Cancer research; Membrane","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001233939,0.0001958634,0.0001868317,0.0002544563,0.0002148459,0.0004144447,0.0001203561,0.0002408458,0.0009102061],"category_scores_gemma":[0.0001506399,0.00009553627,0.0001666202,0.0001746617,0.0002068794,0.0002660895,0.000186085,0.0004994193,0.000259226],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004450245,"about_ca_system_score_gemma":0.0001895458,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006175313,"about_ca_topic_score_gemma":0.0008481317,"domain_scores_codex":[0.9999132,0.00001180261,0.000007279425,0.00002003743,0.00002055649,0.00002716468],"domain_scores_gemma":[0.9999392,0.00000779768,0.00001572447,0.000004115379,0.00001504132,0.00001817734],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001892539,0.00001597125,0.0006786137,0.00002943271,0.00000536717,0.00005173718,0.00001850218,0.00004633937,0.9954407,0.000275762,0.00008523277,0.003163019],"study_design_scores_gemma":[0.00006754988,0.0002475778,0.02161761,0.00001050692,0.00005193989,0.0002480332,0.0001069922,0.001543562,0.964983,0.000395457,0.01071581,0.0000118729],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9844397,0.00727658,0.004121227,0.0004651953,0.00009017946,0.00004153392,0.0003311703,0.0001336956,0.003100709],"genre_scores_gemma":[0.9947208,0.001991571,0.0009533589,0.0001038907,0.00001327885,0.00001968759,0.0001988679,0.00001174206,0.00198678],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009102061,"threshold_uncertainty_score":0.003228903,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008376650906733405,"score_gpt":0.2720719263811968,"score_spread":0.2636952754744634,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}