{"id":"W2950880342","doi":"10.1136/annrheumdis-2019-eular.1921","title":"FRI0462 UNDERSTANDING MEDIATORS OF PAIN REDUCTION IN PSORIATIC ARTHRITIS PATIENTS TREATED WITH TOFACITINIB: ROLE OF INFLAMMATION","year":2019,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Spondyloarthritis Studies and Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Pfizer (Canada)","funders":"Gilead Sciences; Amgen; Pfizer; Genentech; Celgene; AstraZeneca; Eli Lilly and Company; Bristol-Myers Squibb","keywords":"Tofacitinib; Medicine; Psoriatic arthritis; Placebo; Janus kinase inhibitor; Internal medicine; Visual analogue scale; Psoriasis; Arthritis; Population; Physical therapy; Dermatology; Rheumatoid arthritis; Pathology; Alternative medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009851871,0.0004668914,0.0008226301,0.0003841168,0.0002302636,0.001502622,0.0004154639,0.000743417,0.00502964],"category_scores_gemma":[0.001498146,0.0001713062,0.0008230229,0.0003121096,0.0003159539,0.0008461939,0.0003965219,0.0014698,0.000535498],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007270635,"about_ca_system_score_gemma":0.001196422,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002171214,"about_ca_topic_score_gemma":0.004379121,"domain_scores_codex":[0.999382,0.0002229188,0.00005256948,0.00005968207,0.0001702724,0.0001126183],"domain_scores_gemma":[0.9995143,0.0001455673,0.000175125,0.00001876662,0.0000889032,0.00005724017],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.01971185,0.001923735,0.0357962,0.008477391,0.003036648,0.0007663809,0.0006621385,0.001323183,0.05930365,0.006141221,0.02708585,0.8357718],"study_design_scores_gemma":[0.01470634,0.02911032,0.4686949,0.007254305,0.01130231,0.004003046,0.002748795,0.007540526,0.03720128,0.01677715,0.4003031,0.0003579115],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"review","genre_gemma":"empirical","genre_scores_codex":[0.2840898,0.6534975,0.002278907,0.02830326,0.001924442,0.0002075001,0.001937968,0.0001288395,0.02763168],"genre_scores_gemma":[0.8161651,0.165429,0.003057214,0.006135323,0.002072179,0.0001827658,0.000926756,0.00002183062,0.006009825],"genre_candidate":"empirical","genre_consensus":null,"teacher_disagreement_score":0.00502964,"threshold_uncertainty_score":0.01682585,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01663464922587403,"score_gpt":0.2433698150448088,"score_spread":0.2267351658189348,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}