{"id":"W2950887102","doi":"10.1021/ol005928a","title":"Diastereoselective Formation of 5-Vinylcyclopentenes from 1,6-Enynes:  Cobalt-Mediated C−H Allylic Activation and Formal 5-Endo-Dig Cyclization","year":2000,"lang":"en","type":"article","venue":"Organic Letters","topic":"Catalytic C–H Functionalization Methods","field":"Chemistry","cited_by":19,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"","keywords":"Allylic rearrangement; Chemistry; Trimethylsilyl; Yield (engineering); Cobalt; Intramolecular force; Medicinal chemistry; Dig; Thermal decomposition; Stereochemistry; Catalysis; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000157002,0.0005705914,0.0002487473,0.0001590435,0.0001679289,0.0003377782,0.0002728252,0.0003042554,0.001679136],"category_scores_gemma":[0.0001725362,0.0001628219,0.0001989438,0.0001178281,0.000237314,0.0002722958,0.000330531,0.0005337595,0.0006636154],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002976464,"about_ca_system_score_gemma":0.000281659,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000388952,"about_ca_topic_score_gemma":0.001196513,"domain_scores_codex":[0.9998416,0.00001736393,0.00001037992,0.00003294933,0.00002794113,0.00006986544],"domain_scores_gemma":[0.9999175,0.00001143163,0.00001968165,0.00001084867,0.00001025495,0.00003032204],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009371596,0.00005009083,0.0001819584,0.0001103262,0.00001361688,0.0002643681,0.000115474,0.0002746512,0.9916502,0.001194093,0.000159819,0.005891745],"study_design_scores_gemma":[0.00001689102,0.0001336524,0.0004514914,0.000003885238,0.000005866384,0.0001558717,0.00002262867,0.0002432373,0.9958621,0.00007009684,0.003027136,0.000007093925],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9737473,0.001748787,0.01054302,0.0001312774,0.00009942734,0.0001202825,0.0003153713,0.0001937909,0.01310073],"genre_scores_gemma":[0.9913998,0.0007866523,0.003502017,0.00002906393,0.000009066098,0.00002662464,0.0002272836,0.00002767268,0.003991734],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001679136,"threshold_uncertainty_score":0.005617201,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01016157122631804,"score_gpt":0.2240664450275217,"score_spread":0.2139048738012036,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}