{"id":"W2950914207","doi":"10.1007/s40257-019-00454-6","title":"Long-Term Effectiveness and Safety of Up to 48 Weeks’ Treatment with Topical Adapalene 0.3%/Benzoyl Peroxide 2.5% Gel in the Prevention and Reduction of Atrophic Acne Scars in Moderate and Severe Facial Acne","year":2019,"lang":"en","type":"article","venue":"American Journal of Clinical Dermatology","topic":"Acne and Rosacea Treatments and Effects","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":false,"ca_institutions":"Lynde Centre for Dermatology; Windsor Clinical Research; Occupational Cancer Research Centre; Western University; Innovaderm (Canada)","funders":"Galderma","keywords":"Medicine; Acne; Adapalene; Tolerability; Benzoyl peroxide; Dermatology; Scars; Acne scars; Surgery; Adverse effect; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003464232,0.0001294146,0.0009981018,0.0001060855,0.00002070101,0.000004537115,0.00004035174,0.00008218829,0.00000470626],"category_scores_gemma":[0.00003458101,0.00007150039,0.000075946,0.0001114432,0.0002836926,0.00007120171,0.00002321267,0.0001855669,4.554858e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002460379,"about_ca_system_score_gemma":0.00009007091,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005812587,"about_ca_topic_score_gemma":0.00004433511,"domain_scores_codex":[0.9984086,0.0005089444,0.0006399928,0.0001791835,0.0001245195,0.0001387745],"domain_scores_gemma":[0.9990277,0.0003661108,0.0003442201,0.0001106211,0.00005391922,0.00009746104],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.01305132,0.0003776813,0.8677002,0.0001170438,0.0001943254,0.0001330244,0.0006851819,0.00003156942,0.0005981851,0.00002273041,0.000002255847,0.1170865],"study_design_scores_gemma":[0.008780514,0.01006501,0.9755191,0.0004020291,0.0001884797,0.003838641,0.0004814629,0.0000574926,0.0005352142,0.00005077393,0.00001227603,0.00006897998],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.997941,0.0003958577,0.00008631194,0.001036515,0.00007868127,0.0004411754,0.000002527898,0.000001312541,0.00001667642],"genre_scores_gemma":[0.9983611,0.001306361,0.0002164709,0.00005334437,0.00003358253,0.000004707238,0.000001914763,0.000006754968,0.00001576343],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1170175,"threshold_uncertainty_score":0.2915701,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01885888520017651,"score_gpt":0.3446266133717555,"score_spread":0.325767728171579,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}