{"id":"W2950914207","doi":"10.1007/s40257-019-00454-6","title":"Long-Term Effectiveness and Safety of Up to 48 Weeks’ Treatment with Topical Adapalene 0.3%/Benzoyl Peroxide 2.5% Gel in the Prevention and Reduction of Atrophic Acne Scars in Moderate and Severe Facial Acne","year":2019,"lang":"en","type":"article","venue":"American Journal of Clinical Dermatology","topic":"Acne and Rosacea Treatments and Effects","field":"Medicine","cited_by":33,"is_retracted":false,"has_abstract":false,"ca_institutions":"Lynde Centre for Dermatology; Windsor Clinical Research; Occupational Cancer Research Centre; Western University; Innovaderm (Canada)","funders":"Galderma","keywords":"Medicine; Acne; Adapalene; Tolerability; Benzoyl peroxide; Dermatology; Scars; Acne scars; Surgery; Adverse effect; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005029239,0.0003093471,0.0007421199,0.0002145618,0.0002994553,0.0003070394,0.0003229752,0.0006164109,0.002992474],"category_scores_gemma":[0.0005792414,0.000161877,0.0009416116,0.0001672341,0.0003535132,0.0006396573,0.0001908452,0.001085861,0.0005458278],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001630177,"about_ca_system_score_gemma":0.0001562388,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006072312,"about_ca_topic_score_gemma":0.0009114271,"domain_scores_codex":[0.9997047,0.00009190432,0.0000266421,0.00005131854,0.00004036344,0.00008496381],"domain_scores_gemma":[0.9996523,0.00008117741,0.00005866331,0.00007620096,0.00005213311,0.0000797043],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"observational","study_design_scores_codex":[0.3305528,0.04676437,0.01761669,0.0007761911,0.001122495,0.0005707729,0.0004843809,0.001221631,0.2773938,0.000193949,0.001206594,0.3220963],"study_design_scores_gemma":[0.0141826,0.6153664,0.2404516,0.0001353765,0.002433838,0.0009927256,0.0004253708,0.001960587,0.1160452,0.000309756,0.007596195,0.0001002793],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961106,0.002846194,0.0001420256,0.000063147,0.00006241441,0.00003298454,0.000123763,0.00001254775,0.0006063283],"genre_scores_gemma":[0.9977192,0.0006065075,0.0001027763,0.00003992823,0.00005167102,0.00003782987,0.0001613455,0.000004045952,0.001276627],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002992474,"threshold_uncertainty_score":0.01001084,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01885888520017651,"score_gpt":0.3446266133717555,"score_spread":0.325767728171579,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}