{"id":"W2950922392","doi":"10.1002/chin.200628024","title":"Asymmetric Synthesis of All‐Carbon Benzylic Quaternary Stereocenters via Cu‐Catalyzed Conjugate Addition of Dialkylzinc Reagents to 5‐(1‐Arylalkylidene) Meldrum′s Acids.","year":2006,"lang":"en","type":"article","venue":"ChemInform","topic":"Cyclopropane Reaction Mechanisms","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Waterloo","funders":"","keywords":"Chemistry; Stereocenter; Conjugate; Reagent; Catalysis; Quaternary carbon; Combinatorial chemistry; Carbon fibers; Organic chemistry; Enantioselective synthesis; Algorithm","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001844861,0.0003901919,0.0006260079,0.0003829906,0.00004296859,0.00002459501,0.0004741101,0.0002556503,0.0005011025],"category_scores_gemma":[0.0002189592,0.0004100662,0.0002684826,0.0004705789,0.00007178317,0.0002499977,0.0001992874,0.0001801654,0.00006123589],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002692733,"about_ca_system_score_gemma":0.00006617104,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009128688,"about_ca_topic_score_gemma":0.0001104712,"domain_scores_codex":[0.9973498,0.000002714227,0.001065414,0.0004277133,0.0006850644,0.0004692822],"domain_scores_gemma":[0.9979038,0.0002178314,0.0007482297,0.0007347378,0.0001984874,0.0001969271],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003370918,0.0002432234,0.00104077,0.001043575,0.0001775648,0.00001717151,0.0003032344,0.000004960033,0.8254747,0.00002454255,0.001045438,0.1702877],"study_design_scores_gemma":[0.0007594192,0.00004178648,0.0005873039,0.0002919998,0.0001483187,0.00002663795,0.0002623226,0.00006502253,0.994584,0.00007057616,0.002797193,0.0003654715],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7969431,0.0001379402,0.00002286464,0.00004492371,0.0001898863,0.0002812996,0.0003333151,0.0001375429,0.2019091],"genre_scores_gemma":[0.9973444,0.00008300052,0.0002495759,0.0000391082,0.0001552913,0.0000922609,0.0007011669,0.00006662097,0.001268622],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2006405,"threshold_uncertainty_score":0.9998351,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01007112477650938,"score_gpt":0.2204734851418468,"score_spread":0.2104023603653374,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}