{"id":"W2950979312","doi":"10.1016/j.biotechadv.2019.06.008","title":"Betulin and its derivatives as novel compounds with different pharmacological effects","year":2019,"lang":"en","type":"review","venue":"Biotechnology Advances","topic":"Natural product bioactivities and synthesis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":266,"is_retracted":false,"has_abstract":false,"ca_institutions":"CancerCare Manitoba; St. Boniface Hospital; Children's Hospital Research Institute of Manitoba; University of Manitoba","funders":"Research Manitoba","keywords":"Betulin; Betulinic acid; Pharmacology; Chemistry; Medicine; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.00006913984,0.0005489495,0.001160906,0.0001083742,0.0001102683,0.00002095075,0.0003657075,0.001059782,0.000008121484],"category_scores_gemma":[0.0001634427,0.0003327222,0.0001519347,0.0001313459,0.0003801621,0.000008614042,0.0003119337,0.0004843676,0.00001044877],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002578503,"about_ca_system_score_gemma":0.00006558949,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001058645,"about_ca_topic_score_gemma":0.000003020953,"domain_scores_codex":[0.9983134,0.00009081637,0.0002482688,0.0008798909,0.0001106522,0.0003569513],"domain_scores_gemma":[0.9991586,0.0001668427,0.0002682363,0.0003110504,0.00003540147,0.00005989868],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001022863,0.0001506404,0.000007241847,0.005700022,0.0006576027,0.00001209557,0.000004030394,2.99354e-7,0.04935035,0.0006661119,0.00008255168,0.9432667],"study_design_scores_gemma":[0.0003174967,0.000845764,0.000004664414,0.0008440411,0.000374054,0.0001370616,0.00001280148,9.724216e-7,0.1224377,0.00003091433,0.8745311,0.00046344],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.008436749,0.989953,0.00008051461,0.0002451406,0.0002385583,0.0008350076,0.00005004831,0.00005670206,0.0001042587],"genre_scores_gemma":[0.009908096,0.9888602,0.000373053,0.00007476724,0.0001608538,0.0001080933,0.00009257063,0.00004084049,0.0003815184],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9428033,"threshold_uncertainty_score":0.9999125,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0226161065196697,"score_gpt":0.3117220585646576,"score_spread":0.2891059520449879,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}