{"id":"W2950979312","doi":"10.1016/j.biotechadv.2019.06.008","title":"Betulin and its derivatives as novel compounds with different pharmacological effects","year":2019,"lang":"en","type":"review","venue":"Biotechnology Advances","topic":"Natural product bioactivities and synthesis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":266,"is_retracted":false,"has_abstract":false,"ca_institutions":"CancerCare Manitoba; St. Boniface Hospital; Children's Hospital Research Institute of Manitoba; University of Manitoba","funders":"Research Manitoba","keywords":"Betulin; Betulinic acid; Pharmacology; Chemistry; Medicine; Biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003502514,0.0009554146,0.001014194,0.001328291,0.0001739028,0.0006944573,0.0005777898,0.0005903398,0.002985174],"category_scores_gemma":[0.0002987675,0.0002933661,0.0002696786,0.00165689,0.0003780262,0.0008599079,0.0004924848,0.001621362,0.001621686],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003935015,"about_ca_system_score_gemma":0.0004072119,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004302348,"about_ca_topic_score_gemma":0.001215721,"domain_scores_codex":[0.9999121,0.00001139917,0.000008664909,0.00002012771,0.00003278139,0.00001486007],"domain_scores_gemma":[0.9999311,0.00002917773,0.00001331535,0.000003762072,0.00001214795,0.00001039014],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001916272,0.0001660012,0.0001027,0.009722684,0.00008601243,0.0002713714,0.00004696872,0.0007898518,0.01998567,0.008470099,0.01532655,0.9448404],"study_design_scores_gemma":[0.00005701461,0.0002267034,0.0005642542,0.0009726546,0.0001329502,0.0007683321,0.00003256147,0.0002040907,0.006310771,0.002498044,0.988206,0.00002665758],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0009583951,0.9948846,0.0006210069,0.0001820798,0.0003264057,0.00001046908,0.0000499688,0.00001819283,0.002948871],"genre_scores_gemma":[0.004343406,0.9916931,0.0006680258,0.0002816083,0.0002352668,0.00001817115,0.00008889876,0.000005107351,0.002666411],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002985174,"threshold_uncertainty_score":0.009986401,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0226161065196697,"score_gpt":0.3117220585646576,"score_spread":0.2891059520449879,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}