{"id":"W2950988732","doi":"10.1093/nar/gkz514","title":"A Fanci knockout mouse model reveals common and distinct functions for FANCI and FANCD2","year":2019,"lang":"en","type":"article","venue":"Nucleic Acids Research","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":54,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Institute for Research in Immunology and Cancer; Université Laval","funders":"National Cancer Institute; National Heart, Lung, and Blood Institute; National Institutes of Health; Canadian Institutes of Health Research; Fanconi Anemia Research Fund","keywords":"FANCD2; Biology; FANCA; Homologous recombination; Fanconi anemia; Genetics; Phenotype; DNA repair; Mutation; Meiosis; Epistasis; Cell biology; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002136786,0.0009546261,0.0003862992,0.00131223,0.0003989302,0.0003706192,0.0005129659,0.0009708413,0.004025509],"category_scores_gemma":[0.0001374402,0.0004266452,0.0003982043,0.0004279597,0.0004816243,0.0004057045,0.0003931672,0.00108786,0.0007459596],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004649588,"about_ca_system_score_gemma":0.0003884153,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007421502,"about_ca_topic_score_gemma":0.001134493,"domain_scores_codex":[0.9997134,0.0000288494,0.00003018989,0.0001071699,0.00007289421,0.00004756671],"domain_scores_gemma":[0.9998167,0.00001516727,0.00005643455,0.00002426808,0.00001356668,0.00007392144],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002327033,0.0000578313,0.000300572,0.00004680785,0.00001002468,0.0003573325,0.00002570305,0.00008397851,0.9952754,0.001121099,0.0002325194,0.002256145],"study_design_scores_gemma":[0.000235511,0.0009505171,0.01386837,0.00007286717,0.0001389664,0.008855469,0.00008945489,0.002688414,0.936743,0.001220284,0.03508207,0.00005523405],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9581273,0.003411792,0.02464803,0.0006706553,0.0001583774,0.0002210191,0.003908622,0.001420322,0.007433774],"genre_scores_gemma":[0.9408811,0.002851231,0.02094807,0.0003458085,0.00004168593,0.0005227834,0.004925382,0.0002831571,0.0292007],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004025509,"threshold_uncertainty_score":0.01346672,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03470216080561837,"score_gpt":0.3313673039362103,"score_spread":0.2966651431305919,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}