{"id":"W2951140459","doi":"10.1021/jo010873r","title":"Diastereoselective Synthesis of 2,3,5-Trisubstituted Tetrahydrofurans via Cyclofunctionalization Reactions. Evidence of Stereoelectronic Effects","year":2001,"lang":"en","type":"article","venue":"The Journal of Organic Chemistry","topic":"Microbial Metabolism and Applications","field":"Biochemistry, Genetics and Molecular Biology","cited_by":16,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"","keywords":"Chemistry; Stereochemistry; Stereoselectivity; Computational chemistry; Organic chemistry; Combinatorial chemistry; Catalysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001668846,0.0004092262,0.0001639151,0.0001685524,0.0001372095,0.0002072376,0.0002262056,0.000179935,0.00163485],"category_scores_gemma":[0.0001913492,0.0001145478,0.0001821405,0.000171572,0.0001670445,0.0002545903,0.0002016094,0.0003937813,0.0005194655],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003416593,"about_ca_system_score_gemma":0.0003684217,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006445285,"about_ca_topic_score_gemma":0.00179921,"domain_scores_codex":[0.9999052,0.00001611035,0.000007627532,0.00002072062,0.00001608134,0.00003416132],"domain_scores_gemma":[0.9998944,0.00002004103,0.00002582519,0.0000197764,0.00001739965,0.00002255503],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009390001,0.00004159185,0.0001581254,0.00008710093,0.00000979694,0.0002219577,0.00008697028,0.0006037295,0.9878871,0.001628914,0.0001828382,0.008997967],"study_design_scores_gemma":[0.000009602729,0.0001798645,0.0003992205,0.000003851698,0.000008917719,0.0001816469,0.00001830717,0.0005263121,0.9953358,0.000141877,0.003188005,0.000006661563],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.958666,0.002119584,0.02260194,0.000197861,0.0001112954,0.0001279824,0.00080607,0.0002246057,0.01514465],"genre_scores_gemma":[0.9807366,0.001320411,0.01396167,0.00004926794,0.000008053516,0.00003561224,0.0003070057,0.00004063169,0.003540726],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00163485,"threshold_uncertainty_score":0.005469084,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006263220756657564,"score_gpt":0.2292958628423708,"score_spread":0.2230326420857132,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}