{"id":"W2951174368","doi":"10.1016/j.mrgentox.2019.06.003","title":"The mutagenic activity of select azo compounds in MutaMouse target tissues in vivo and primary hepatocytes in vitro","year":2019,"lang":"en","type":"article","venue":"Mutation Research/Genetic Toxicology and Environmental Mutagenesis","topic":"Carcinogens and Genotoxicity Assessment","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Canada; University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; Health Canada","keywords":"In vivo; Chemistry; In vitro; Metabolite; Carcinogen; Mutagen; Benzidine; Biochemistry; Hepatocyte; Pharmacology; Molecular biology; Biology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002708477,0.0004799542,0.0003412607,0.0004615258,0.0001636754,0.0002083081,0.0001270381,0.0002494824,0.00196585],"category_scores_gemma":[0.0001592825,0.0001932342,0.0002541949,0.0002106686,0.0001956445,0.0001347581,0.0002120982,0.0003934458,0.0004460895],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001951733,"about_ca_system_score_gemma":0.0001796132,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001249321,"about_ca_topic_score_gemma":0.002571224,"domain_scores_codex":[0.9997852,0.00006820244,0.00002124372,0.00003957978,0.00005258729,0.00003324257],"domain_scores_gemma":[0.9997941,0.00006145768,0.00003494378,0.00002238804,0.00005180574,0.00003534381],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002018944,0.00003784259,0.0006396842,0.00003934628,0.000008774202,0.00005165385,0.00002166601,0.00005204394,0.998069,0.00002414304,0.00001651657,0.0008374954],"study_design_scores_gemma":[0.00001420958,0.002457405,0.009921123,0.000003506983,0.00002853117,0.0002200522,0.00006585689,0.0002383047,0.986448,0.00002190116,0.0005763057,0.000004631285],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9915671,0.002376971,0.003206656,0.00005285109,0.0000278865,0.00006141895,0.000412828,0.00006485599,0.002229484],"genre_scores_gemma":[0.9890926,0.001873304,0.002658713,0.00007039971,0.00001601366,0.00007748866,0.0007759223,0.00001608704,0.005419505],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00196585,"threshold_uncertainty_score":0.006576419,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01013080055014465,"score_gpt":0.2671325598521296,"score_spread":0.257001759301985,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}