{"id":"W2951174368","doi":"10.1016/j.mrgentox.2019.06.003","title":"The mutagenic activity of select azo compounds in MutaMouse target tissues in vivo and primary hepatocytes in vitro","year":2019,"lang":"en","type":"article","venue":"Mutation Research/Genetic Toxicology and Environmental Mutagenesis","topic":"Carcinogens and Genotoxicity Assessment","field":"Biochemistry, Genetics and Molecular Biology","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Canada; University of Ottawa","funders":"Natural Sciences and Engineering Research Council of Canada; Health Canada","keywords":"In vivo; Chemistry; In vitro; Metabolite; Carcinogen; Mutagen; Benzidine; Biochemistry; Hepatocyte; Pharmacology; Molecular biology; Biology; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007512041,0.0001690788,0.0002613259,0.0001998401,0.0001001514,0.00002246927,0.0001450954,0.0001949223,0.00004375226],"category_scores_gemma":[0.00003130897,0.0001568932,0.0000384483,0.0001738455,0.0004211644,0.00001103418,0.0002465112,0.0002013441,0.000003247053],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001241571,"about_ca_system_score_gemma":0.00006757372,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002596874,"about_ca_topic_score_gemma":0.0008752518,"domain_scores_codex":[0.9980341,0.000538567,0.0003077509,0.0004729999,0.0002287259,0.0004178515],"domain_scores_gemma":[0.9994129,0.0001915832,0.00007239306,0.0002429817,0.00001028292,0.0000698701],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000449518,0.0001849,0.1816958,0.00003633148,0.00001962343,0.0000239172,0.0002109748,0.0004013104,0.8123574,0.000003332086,0.000008515271,0.004608358],"study_design_scores_gemma":[0.000836176,0.0003613279,0.4789765,0.000006674436,0.000003866851,0.00001882457,0.0003799102,0.0007770715,0.5182033,0.00005076007,0.000276283,0.000109222],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964904,0.002480975,0.00001755048,0.0001298004,0.00003447213,0.0007053825,0.00004402424,0.000002810864,0.00009453796],"genre_scores_gemma":[0.9974274,0.001859515,0.0002757532,0.00005139824,0.00001577559,0.0001074218,0.00003446398,0.00001927464,0.0002090037],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2972807,"threshold_uncertainty_score":0.6397918,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01013080055014465,"score_gpt":0.2671325598521296,"score_spread":0.257001759301985,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}