{"id":"W2951202717","doi":"10.1002/chin.200251225","title":"1‐(Bicyclopiperazinyl)ethylindoles and 1‐(Homopiperazinyl)ethylindoles as Highly Selective and Potent 5‐HT<sub>7</sub> Receptor Ligands.","year":2002,"lang":"en","type":"article","venue":"ChemInform","topic":"Receptor Mechanisms and Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Cantox Health Sciences International","funders":"","keywords":"Chemistry; 5-HT receptor; Stereochemistry; Combinatorial chemistry; Receptor; Biochemistry; Serotonin","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001427425,0.0002311282,0.0002339314,0.0001629729,0.00009996472,0.0001767787,0.0004124816,0.0003011565,0.003713232],"category_scores_gemma":[0.0001134612,0.0001576529,0.000112342,0.0001443499,0.000183454,0.0002140789,0.0002087738,0.000502524,0.001181907],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002520495,"about_ca_system_score_gemma":0.0001536611,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000376763,"about_ca_topic_score_gemma":0.00215326,"domain_scores_codex":[0.9999005,0.00002485125,0.000003816627,0.00001044721,0.00002631011,0.00003403761],"domain_scores_gemma":[0.9999721,0.000005987096,0.000007435211,0.000002350061,0.000003555403,0.000008556504],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001186218,0.0001881441,0.0002143919,0.0003998166,0.00004043784,0.0003356297,0.00006798738,0.0007292611,0.9203871,0.003680611,0.00325153,0.06951883],"study_design_scores_gemma":[0.0005985227,0.003887374,0.005299303,0.00005527889,0.00009698777,0.001890731,0.0000629978,0.002044925,0.919445,0.0006176644,0.0659623,0.00003882392],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8761686,0.06112901,0.01409399,0.0006619832,0.0003034405,0.0002434825,0.001132243,0.0006131377,0.04565424],"genre_scores_gemma":[0.9501021,0.01908649,0.006928166,0.0004596341,0.00006825247,0.0001717242,0.001314701,0.0000435978,0.02182523],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003713232,"threshold_uncertainty_score":0.01242197,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006992730685161879,"score_gpt":0.2009004774752193,"score_spread":0.1939077467900574,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}