{"id":"W2951224778","doi":"10.1016/j.euroneuro.2017.08.003","title":"MITOCHONDRIAL DNA SNPS ASSOCIATED WITH SCHIZOPHRENIA EXHIBIT HIGHLY VARIABLE INTER-ALLELIC HAPLOGROUP AFFILIATION AND NUCLEAR GENOGEOGRAPHIC AFFINITY: BI-GENOMIC LINKAGE DISEQUILIBRIUM RAISES MAJOR CONCERN FOR LINK TO DISEASE","year":2019,"lang":"en","type":"article","venue":"European Neuropsychopharmacology","topic":"Mitochondrial Function and Pathology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":0,"is_retracted":false,"has_abstract":false,"ca_institutions":"Centre for Addiction and Mental Health","funders":"","keywords":"Mitochondrial DNA; Single-nucleotide polymorphism; Genetics; Biology; Haplogroup; Population; Linkage disequilibrium; Nuclear DNA; Disease; Nuclear gene; Haplotype; Allele; Medicine; Gene; Genotype; Pathology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006436902,0.000239212,0.0003092074,0.0008246074,0.0006529876,0.0004759151,0.0002720747,0.0003286194,0.004016642],"category_scores_gemma":[0.001327314,0.0001347669,0.000159573,0.001059623,0.000364273,0.0002409363,0.0005821779,0.0003295179,0.000329741],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001305999,"about_ca_system_score_gemma":0.0001813901,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001552606,"about_ca_topic_score_gemma":0.00383451,"domain_scores_codex":[0.9994453,0.0002226847,0.00005703721,0.0001368849,0.00006377353,0.00007431099],"domain_scores_gemma":[0.9989268,0.0004100954,0.0003627354,0.0001059589,0.00008307948,0.0001112563],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001015158,0.000067297,0.9047982,0.0000469352,0.0004078302,0.0006147582,0.001483931,0.0002202024,0.07803143,0.001139009,0.0001674612,0.01200789],"study_design_scores_gemma":[0.00001876017,0.000133792,0.9937364,0.00001296329,0.0000680694,0.001000717,0.0007963578,0.0003800385,0.002006961,0.001289385,0.0005463381,0.00001018239],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9985115,0.0001243643,0.0006074402,0.00006782637,0.000003920216,0.000002169756,0.000184476,0.000004685579,0.000493614],"genre_scores_gemma":[0.9995203,0.00003451358,0.0001748307,0.00001501168,0.000002886465,0.00000175412,0.00009542108,0.000003355349,0.0001518867],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.004016642,"threshold_uncertainty_score":0.01343697,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01132380148341373,"score_gpt":0.2355697003775775,"score_spread":0.2242458988941638,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}