{"id":"W2951229452","doi":"10.1097/01.hs9.0000562388.60660.bc","title":"PS1023 MUTANT IDH1 INHIBITOR IVOSIDENIB (AG‐120) IN COMBINATION WITH AZACITIDINE FOR NEWLY DIAGNOSED ACUTE MYELOID LEUKEMIA","year":2019,"lang":"en","type":"article","venue":"HemaSphere","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre","funders":"","keywords":"Myeloid leukemia; Medicine; Internal medicine; Gastroenterology; Isocitrate dehydrogenase; IDH1; Adverse effect; Azacitidine; Bone marrow; Nausea; Leukemia; Cytarabine; Chemistry; Mutant","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003623618,0.0004068348,0.0009634891,0.0002930036,0.0001784254,0.0003757121,0.0004334387,0.0002647331,0.001400108],"category_scores_gemma":[0.000349286,0.0001869251,0.0003688206,0.0002823058,0.0002368838,0.0002303138,0.0002150031,0.0009461625,0.0003036185],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006431183,"about_ca_system_score_gemma":0.0005984614,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007237676,"about_ca_topic_score_gemma":0.003516553,"domain_scores_codex":[0.9998604,0.00004776655,0.00001299888,0.00002540625,0.00002780563,0.00002565026],"domain_scores_gemma":[0.9998295,0.0000327205,0.00003164525,0.00001319453,0.00001037114,0.00008241276],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.1857566,0.01621012,0.04865446,0.001325391,0.001330313,0.002993569,0.0005226576,0.004158044,0.2976632,0.0005436635,0.007657542,0.4331844],"study_design_scores_gemma":[0.115092,0.4301573,0.2747577,0.0002469468,0.002300625,0.01057215,0.0003608477,0.008722832,0.1104406,0.0007458037,0.04649678,0.0001065077],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9922662,0.003905619,0.0004197888,0.0002590739,0.00005544312,0.0004636241,0.0004217792,0.00006741874,0.002140831],"genre_scores_gemma":[0.9956759,0.001585887,0.0007678625,0.0001540654,0.00003563838,0.000165282,0.0006225614,0.000009435137,0.0009835293],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001400108,"threshold_uncertainty_score":0.004683852,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01306010377929663,"score_gpt":0.2728298898142398,"score_spread":0.2597697860349432,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}