{"id":"W2951237712","doi":"10.1021/ol802357e","title":"Bifunctional Reactivity of Cu<sup>I</sup>: Sequential Ring Opening/N-Arylation","year":2008,"lang":"en","type":"article","venue":"Organic Letters","topic":"Chemical Synthesis and Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"Centre National de la Recherche Scientifique","keywords":"Chemistry; Bifunctional; Reactivity (psychology); Ring (chemistry); Combinatorial chemistry; Medicinal chemistry; Organic chemistry; Catalysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008155075,0.00009377669,0.0001265402,0.00002875249,0.00007176649,0.000006366306,0.00009991206,0.00007161378,0.0002093943],"category_scores_gemma":[0.00006468098,0.00009046899,0.0001132699,0.0001008435,0.00006460612,0.000007104791,0.00006550478,0.00006427396,0.0000134378],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002280405,"about_ca_system_score_gemma":0.00002854061,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007967826,"about_ca_topic_score_gemma":0.000004716348,"domain_scores_codex":[0.9993203,0.00002766269,0.0001560239,0.000229213,0.0001391763,0.0001276247],"domain_scores_gemma":[0.999657,0.00001387822,0.0000769559,0.0001831262,0.00002897131,0.00004003211],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002173464,0.00003091803,0.007447712,0.000004736579,0.00006382487,0.000002506823,0.00002626868,0.0001111712,0.9909897,0.000003797126,0.0009728747,0.0003247746],"study_design_scores_gemma":[0.0002188303,0.00001740311,0.003503706,0.000005596666,0.00002988586,0.00001938013,0.00001116053,0.0002241464,0.9942401,0.000004113473,0.001614876,0.0001107983],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963049,0.00003812358,0.002840822,0.0005355604,0.0000286595,0.00003559225,0.000005673498,0.000008302694,0.0002023162],"genre_scores_gemma":[0.998975,0.00002940419,0.0002772482,0.0003033938,0.000257566,0.00000241225,0.00007402016,0.00001399734,0.00006694972],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003944006,"threshold_uncertainty_score":0.3689218,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01163556756595346,"score_gpt":0.2115990379580957,"score_spread":0.1999634703921423,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}