{"id":"W2951238591","doi":"10.1016/j.exphem.2019.06.001","title":"Remission clone in acute myeloid leukemia shows growth advantage after chemotherapy but is distinct from leukemic clone","year":2019,"lang":"en","type":"article","venue":"Experimental Hematology","topic":"Acute Myeloid Leukemia Research","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":false,"ca_institutions":"Princess Margaret Cancer Centre; University of Toronto","funders":"Natural Sciences and Engineering Research Council of Canada; National Research Foundation of Korea; Ministry of Health and Welfare","keywords":"clone (Java method); Myeloid leukemia; Cancer research; Chemotherapy; Somatic evolution in cancer; Leukemia; Biology; Myeloid; Medicine; Oncology; Immunology; Gene; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0002100995,0.0005962225,0.001284345,0.0003332677,0.00007435584,0.00002871257,0.0004299468,0.0005735131,0.01057865],"category_scores_gemma":[0.00003849155,0.0005318845,0.0002463574,0.0003707304,0.0002831033,0.0002563034,0.0003869588,0.0009648105,0.001824476],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002688306,"about_ca_system_score_gemma":0.0004937286,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0008709802,"about_ca_topic_score_gemma":0.00001435303,"domain_scores_codex":[0.9961845,0.0001492762,0.0008053987,0.001206706,0.0006148675,0.001039254],"domain_scores_gemma":[0.9981595,0.0001853284,0.0001682549,0.0009923148,0.00007326779,0.0004213029],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.007764088,0.000471363,0.143323,0.0001284533,0.0002238136,0.002114765,0.001882542,2.410478e-7,0.836242,0.0004792929,0.006745233,0.0006251729],"study_design_scores_gemma":[0.01154392,0.0006457065,0.0190287,0.0002774113,0.0000410767,0.001133271,0.001123866,0.0006254693,0.9628788,0.0001929419,0.001948575,0.0005602984],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9867932,0.005745759,0.00004477142,0.001254019,0.0004049347,0.001295049,0.00008994272,0.0001566955,0.004215607],"genre_scores_gemma":[0.9874141,0.0003602238,0.002049439,0.002870071,0.0001910407,0.0002430804,0.0002719764,0.0001504434,0.006449633],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1266368,"threshold_uncertainty_score":0.9997132,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009584824039175115,"score_gpt":0.2976407535147833,"score_spread":0.2880559294756082,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}