{"id":"W2951239749","doi":"10.1021/ol016562k","title":"The Diels−Alder Reactions of Quinone Imine Ketals:  A Versatile Synthesis of Highly Substituted 5-Methoxyindoles","year":2001,"lang":"en","type":"article","venue":"Organic Letters","topic":"Bioactive Compounds and Antitumor Agents","field":"Pharmacology, Toxicology and Pharmaceutics","cited_by":51,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Chemistry; Imine; Quinone; Yield (engineering); Organic chemistry; Diels–Alder reaction; Combinatorial chemistry; Catalysis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005247577,0.0006495626,0.000256387,0.0004006017,0.0002465317,0.00027078,0.0005909199,0.0004647419,0.001837953],"category_scores_gemma":[0.0002421264,0.0003279071,0.0002935762,0.0002751925,0.0003739343,0.0006078253,0.0005365967,0.0007113568,0.0008374371],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002844276,"about_ca_system_score_gemma":0.0001813129,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001739326,"about_ca_topic_score_gemma":0.0005653573,"domain_scores_codex":[0.9998019,0.00004894142,0.00001476661,0.00003171612,0.00004339225,0.00005925234],"domain_scores_gemma":[0.9999194,0.00001433605,0.00002206354,0.00001289042,0.000009244032,0.00002196384],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001913066,0.0001030674,0.0001633074,0.0005242969,0.00003843265,0.0007616524,0.0003716983,0.001448296,0.9638107,0.00683001,0.0008202278,0.024937],"study_design_scores_gemma":[0.00005812648,0.0009118662,0.0008675084,0.00002500962,0.00003368407,0.0009641543,0.00004812943,0.001450599,0.9720765,0.001177446,0.02233387,0.00005310804],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8125598,0.02853803,0.1196222,0.0008404572,0.0005892397,0.0004820971,0.000686634,0.0008998793,0.03578169],"genre_scores_gemma":[0.9634371,0.009360361,0.01997672,0.0001088154,0.00007713246,0.0001200978,0.0002348279,0.00005455782,0.006630392],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001837953,"threshold_uncertainty_score":0.006148517,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.07855024250679302,"score_gpt":0.3689226271181528,"score_spread":0.2903723846113598,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}