{"id":"W2951303008","doi":"10.1021/jo0610154","title":"Synthesis and Stereochemistry of the Antitumor Diterpenoid (+)-Zerumin B","year":2006,"lang":"en","type":"article","venue":"The Journal of Organic Chemistry","topic":"Natural product bioactivities and synthesis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":47,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université Laval","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Chemistry; Stereoselectivity; Terpenoid; Stereochemistry; Aldehyde; Absolute configuration; Reagent; Total synthesis; Organic chemistry; Catalysis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003469563,0.0001352818,0.0001906405,0.000007837355,0.00008403508,0.00001541883,0.0004225264,0.00009835208,0.0001000937],"category_scores_gemma":[0.000240144,0.00007464251,0.0001170174,0.00007532787,0.0002336089,0.000005520643,0.0001592451,0.0001759095,3.980006e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001439282,"about_ca_system_score_gemma":0.00007836185,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000008798272,"about_ca_topic_score_gemma":0.000002593951,"domain_scores_codex":[0.9991934,0.0000473669,0.0003196429,0.000113987,0.0001854431,0.0001401835],"domain_scores_gemma":[0.9990085,0.00006929477,0.0004141967,0.0003789195,0.00009531125,0.00003380042],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000710215,0.00003698652,0.00106225,0.00006208848,0.00004938788,0.000001406949,0.00001596985,0.000001730101,0.9969614,0.00000121545,0.001271875,0.0004647421],"study_design_scores_gemma":[0.0001575873,0.00002018147,0.002063696,0.00004796312,0.00008653981,0.0004444453,0.0001653129,0.000001286498,0.9953423,0.00006295246,0.00151512,0.00009260796],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9960408,0.002411911,0.00002897195,0.0008039291,0.00007152219,0.00004132451,0.00001405618,0.00000190552,0.0005855808],"genre_scores_gemma":[0.9982994,0.0002390077,0.00006895848,0.00003579187,0.0004591638,5.118605e-7,0.000001381575,0.00001522541,0.00088058],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002258581,"threshold_uncertainty_score":0.3043833,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003131549582031614,"score_gpt":0.1803865118688599,"score_spread":0.1772549622868283,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}