{"id":"W2951303938","doi":"10.3987/com-11-12375","title":"Polycyclic Quinolones (Part 2) — Synthesis of Novel 4-Oxo-1,4-dihydrobenzo[h]-[1,3]thiazeto[3,2-a]quinoline Carboxylic Acids via Oxidative Cyclization of the Corresponding 2-Mercaptoquinoline Precursors","year":2011,"lang":"en","type":"article","venue":"Heterocycles","topic":"Phenothiazines and Benzothiazines Synthesis and Activities","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland","funders":"","keywords":"Chemistry; Quinoline; Stereochemistry; Thio-; Vicinal; Medicinal chemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001849531,0.0003686589,0.0005105278,0.0001472324,0.0001384461,0.00001446161,0.000544511,0.0002344754,0.00003782731],"category_scores_gemma":[0.0002246805,0.0002780313,0.0003234461,0.0002576234,0.000415092,0.00002906576,0.0002489308,0.0001271042,0.000002611427],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001826814,"about_ca_system_score_gemma":0.00005172434,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001690087,"about_ca_topic_score_gemma":0.0001579075,"domain_scores_codex":[0.9980446,0.0001365041,0.0006767199,0.0004633988,0.0002824663,0.0003963053],"domain_scores_gemma":[0.9984479,0.00007498336,0.0006271498,0.000679334,0.00009103921,0.00007960441],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003496959,0.0004616185,0.00921007,0.00008884328,0.0001702078,5.172452e-7,0.000544126,0.00004758304,0.9846926,0.0001029042,0.00006916677,0.004262645],"study_design_scores_gemma":[0.0004205013,0.0001894587,0.02119547,0.0001956257,0.0001151121,0.00001636239,0.0002836801,0.0002523038,0.9758468,0.00006002705,0.001108883,0.0003157251],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9961957,0.0009415171,0.001037166,0.00007875671,0.0004141981,0.0002799725,0.0001163926,0.00002559979,0.0009107213],"genre_scores_gemma":[0.9983842,0.000411254,0.0006211118,0.00009593849,0.0002442366,0.00004254276,0.00003135051,0.0000558432,0.0001134593],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0119854,"threshold_uncertainty_score":0.9999672,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02944181825435485,"score_gpt":0.232017632197637,"score_spread":0.2025758139432822,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}