{"id":"W2951303938","doi":"10.3987/com-11-12375","title":"Polycyclic Quinolones (Part 2) — Synthesis of Novel 4-Oxo-1,4-dihydrobenzo[h]-[1,3]thiazeto[3,2-a]quinoline Carboxylic Acids via Oxidative Cyclization of the Corresponding 2-Mercaptoquinoline Precursors","year":2011,"lang":"en","type":"article","venue":"Heterocycles","topic":"Phenothiazines and Benzothiazines Synthesis and Activities","field":"Biochemistry, Genetics and Molecular Biology","cited_by":5,"is_retracted":false,"has_abstract":true,"ca_institutions":"Memorial University of Newfoundland","funders":"","keywords":"Chemistry; Quinoline; Stereochemistry; Thio-; Vicinal; Medicinal chemistry; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001271487,0.0004032355,0.0002690502,0.0002006798,0.0001260353,0.0001947303,0.0002713475,0.0002344001,0.002643904],"category_scores_gemma":[0.0001079284,0.0001307814,0.0002778044,0.0001960551,0.0001744608,0.0002186294,0.0002330843,0.0002778412,0.0008685068],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002016918,"about_ca_system_score_gemma":0.0003212356,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005380241,"about_ca_topic_score_gemma":0.001303005,"domain_scores_codex":[0.9999125,0.00001301275,0.000008987357,0.00001770169,0.00002136266,0.0000265214],"domain_scores_gemma":[0.9999304,0.000005829319,0.00001842813,0.000008401435,0.00001286075,0.00002404336],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00009201552,0.00002702361,0.00009753773,0.0001136406,0.000007778488,0.0001163829,0.00002901866,0.000269861,0.9922636,0.0002159778,0.00007698685,0.006690194],"study_design_scores_gemma":[0.00004299296,0.0009038614,0.001595374,0.00001081084,0.00002164547,0.0003779463,0.00001584289,0.0002269823,0.986516,0.00006349392,0.01021259,0.00001241017],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9609742,0.009785562,0.01988577,0.0001725438,0.0001338057,0.0003703647,0.001124374,0.0002590187,0.007294385],"genre_scores_gemma":[0.9689656,0.006085114,0.01485945,0.0001093376,0.00004043882,0.000144637,0.001111298,0.00003365424,0.008650353],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002643904,"threshold_uncertainty_score":0.008844793,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02944181825435485,"score_gpt":0.232017632197637,"score_spread":0.2025758139432822,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}