{"id":"W2951329724","doi":"10.1113/jp278024","title":"Endocytic recycling of Na<sup>+</sup>–K<sup>+</sup>–Cl<sup>−</sup> cotransporter type 2: importance of exon 4","year":2019,"lang":"en","type":"article","venue":"The Journal of Physiology","topic":"Ion Transport and Channel Regulation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":7,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal; Université Laval; Hôtel-Dieu de Québec","funders":"Kidney Foundation of Canada; Canadian Institutes of Health Research; Université Laval","keywords":"Cotransporter; Endocytic cycle; Exon; Chemistry; Internalization; Symporter; Transmembrane domain; Reabsorption; Cell biology; Biophysics; Biochemistry; Biology; Cell; Transporter; Gene; Endocytosis; Sodium","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006106562,0.0003210956,0.0007324748,0.0001243954,0.00007501362,0.000005646057,0.0005411035,0.0003322785,0.0003294334],"category_scores_gemma":[0.00004234305,0.0002367712,0.0003830031,0.0002070385,0.000246052,0.00002726396,0.00004576876,0.0003743111,0.0000168259],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00003073219,"about_ca_system_score_gemma":0.0001925893,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001864757,"about_ca_topic_score_gemma":0.000003965156,"domain_scores_codex":[0.9976288,0.0002058573,0.001110304,0.0003110372,0.0003186557,0.0004253321],"domain_scores_gemma":[0.9978865,0.00008637346,0.0008773088,0.00058844,0.0004563543,0.0001049685],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001864146,0.0001485816,0.006262643,0.0001731534,0.0003142942,0.000006952116,0.001068873,0.09295164,0.8964022,0.00007672634,0.0003911748,0.0003395578],"study_design_scores_gemma":[0.00593045,0.004870625,0.02733962,0.0004975428,0.0007417627,0.0003039476,0.003158707,0.01562672,0.9326977,0.002164584,0.005729557,0.0009388397],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978454,0.001024077,0.0002653526,0.0001327042,0.000195953,0.0002484285,0.00003333995,0.000007654514,0.0002470688],"genre_scores_gemma":[0.9976625,0.0007866315,0.0001805158,0.0002035192,0.0006035256,0.000002750414,0.0001304336,0.00004658928,0.0003835791],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.07732492,"threshold_uncertainty_score":0.965525,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01093866402717235,"score_gpt":0.2355857989262388,"score_spread":0.2246471348990665,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}