{"id":"W2951415329","doi":"10.1136/annrheumdis-2019-215145","title":"Predictors of disease worsening defined by progression of organ damage in diffuse systemic sclerosis: a European Scleroderma Trials and Research (EUSTAR) analysis","year":2019,"lang":"en","type":"article","venue":"Annals of the Rheumatic Diseases","topic":"Systemic Sclerosis and Related Diseases","field":"Medicine","cited_by":64,"is_retracted":false,"has_abstract":true,"ca_institutions":"St Joseph's Health Care; Western University","funders":"Peking Union Medical College; Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu; Peking Union Medical College Hospital; Bayer; Sapienza Università di Roma; Ege Üniversitesi; Medicinski Fakultet, Sveučilište u Zagrebu; University of Leeds; University of Bern; Universidad de Buenos Aires; Università degli Studi di Cagliari; Sveučilište u Zagrebu; School of Medicine, Stanford University; University of Otago","keywords":"Medicine; Internal medicine; Scleroderma (fungus); Interstitial lung disease; Clinical trial; Imputation (statistics); Pulmonary hypertension; Systemic scleroderma; Cohort; Population; Disease; Lung; Pathology; Missing data","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003103387,0.000249886,0.001540406,0.0006738672,0.00007240051,0.00002888971,0.0003792867,0.00007913131,0.00007384582],"category_scores_gemma":[0.004481834,0.0001511507,0.0005681566,0.001712009,0.0003738179,0.0001267526,0.0002672189,0.000168535,0.00000369478],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002539805,"about_ca_system_score_gemma":0.0001984446,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000112961,"about_ca_topic_score_gemma":0.000002377119,"domain_scores_codex":[0.9939685,0.002375918,0.001741171,0.0004046337,0.001147624,0.0003620985],"domain_scores_gemma":[0.9959167,0.001193812,0.001074484,0.001006866,0.0004093715,0.0003987797],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001368389,0.002320978,0.9698884,0.00468615,0.002041929,0.000003673948,0.001083101,0.0001626725,0.01223695,0.00003596869,0.001997968,0.004173818],"study_design_scores_gemma":[0.003618737,0.0002231721,0.9438918,0.04445808,0.002322964,0.000001222456,0.001836714,0.0008867019,0.002565717,0.00004027073,0.000003320537,0.0001512496],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9712543,0.02642536,0.00000306165,0.0003213897,0.00008263077,0.001431204,0.0003707403,0.00002592753,0.00008531119],"genre_scores_gemma":[0.9949241,0.004781299,0.00001321467,0.00002868705,0.00001803643,0.00003440684,0.00005815581,0.00003899407,0.0001031618],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03977193,"threshold_uncertainty_score":0.6163746,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.09217164975021941,"score_gpt":0.3527032368942012,"score_spread":0.2605315871439818,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}