{"id":"W2951459521","doi":"10.1016/j.eururo.2019.06.006","title":"Surgical Safety of Cytoreductive Nephrectomy Following Sunitinib: Results from the Multicentre, Randomised Controlled Trial of Immediate Versus Deferred Nephrectomy (SURTIME)","year":2019,"lang":"en","type":"article","venue":"European Urology","topic":"Renal cell carcinoma treatment","field":"Medicine","cited_by":40,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Montréal; Queen Elizabeth II Health Sciences Centre; Princess Margaret Cancer Centre","funders":"Ipsen; European Society for Medical Oncology; Astellas Pharma; Eisai; GlaxoSmithKline; Pfizer; AstraZeneca; European Organisation for Research and Treatment of Cancer; Eli Lilly and Company; Bristol-Myers Squibb","keywords":"Medicine; Sunitinib; Renal cell carcinoma; Adverse effect; Common Terminology Criteria for Adverse Events; Nephrectomy; Kidney cancer; Surgery; Randomized controlled trial; Internal medicine; Kidney","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001495299,0.0003508442,0.001542039,0.0001142591,0.00006167662,0.000009145593,0.0002882538,0.0001198215,0.0002145824],"category_scores_gemma":[0.001876064,0.0002240125,0.0008580324,0.0002079529,0.0002145243,0.00005399593,0.0001279302,0.0003790931,0.0001743621],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007697958,"about_ca_system_score_gemma":0.0001841608,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001637683,"about_ca_topic_score_gemma":0.000008811044,"domain_scores_codex":[0.9945449,0.002697373,0.001328122,0.0005435181,0.0004485859,0.0004375303],"domain_scores_gemma":[0.9897145,0.008423694,0.0007120988,0.0008059688,0.0001754237,0.0001683302],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"randomized_trial","study_design_scores_codex":[0.9898946,0.0004435242,0.001054193,0.0000077607,0.001864431,0.0004414722,0.001182575,0.00006919099,0.004186624,0.00002988638,0.0001615847,0.0006641515],"study_design_scores_gemma":[0.9745874,0.003143589,0.0121547,0.00003014037,0.001630887,0.00001716812,0.0003147943,0.000178577,0.001980958,0.000007055182,0.005784394,0.000170341],"study_design_candidate":"randomized_trial","study_design_consensus":"randomized_trial","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9462288,0.0005295231,0.000005868108,0.0005507917,0.001663867,0.004498967,0.00007372424,0.00004845986,0.0464],"genre_scores_gemma":[0.9984804,0.00006770229,0.0001881199,0.00008446662,0.0005376643,0.00003141272,0.000235177,0.00006488959,0.0003101338],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05225163,"threshold_uncertainty_score":0.9134966,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02164275184862141,"score_gpt":0.2596289774364997,"score_spread":0.2379862255878782,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}