{"id":"W2951462850","doi":"10.1021/jo402873e","title":"Pyrimidine-Fused Heterocyclic Frameworks Based on an N4-Arylcytosine Scaffold: Synthesis, Characterization, and PNA Oligomerization of the Fluorescent Cytosine Analogue 5,6-BenzopC","year":2014,"lang":"en","type":"article","venue":"The Journal of Organic Chemistry","topic":"Chemical Synthesis and Analysis","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Fluorescence; Pyrimidine; Scaffold; Chemistry; Cytosine; Combinatorial chemistry; Characterization (materials science); DNA; Biochemistry; Biophysics; Nanotechnology; Materials science; Biology; Computer science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008666651,0.0002632383,0.0001671756,0.0001154338,0.0001462648,0.0001654777,0.0002269869,0.0002581026,0.0006621204],"category_scores_gemma":[0.0001207789,0.00009304829,0.00009896117,0.0001331654,0.0001467198,0.0001712603,0.0001320502,0.0002441029,0.000214915],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003520964,"about_ca_system_score_gemma":0.000234559,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001756394,"about_ca_topic_score_gemma":0.004278064,"domain_scores_codex":[0.9999297,0.00000736385,0.000001796906,0.00001637248,0.00002292255,0.00002194485],"domain_scores_gemma":[0.9999474,0.000007798219,0.00001326031,0.000004442732,0.000008695081,0.00001841911],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002436177,0.00001197496,0.00003510585,0.00002423723,0.000002014793,0.00002974962,0.00001156545,0.0002747585,0.9981251,0.0001500216,0.00001653201,0.001294557],"study_design_scores_gemma":[0.00000480178,0.0001695194,0.0006729819,0.000002969569,0.00000386871,0.00006597931,0.000006394339,0.00104337,0.9965698,0.00002312624,0.001431476,0.000005797672],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9879937,0.001426771,0.007254502,0.00004346684,0.000009644308,0.00005890488,0.0002463196,0.00009582429,0.002870786],"genre_scores_gemma":[0.9892467,0.000848602,0.008104467,0.00002043568,0.000003807036,0.00003651551,0.0002251672,0.00001372874,0.001500586],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001756394,"threshold_uncertainty_score":0.003492296,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004049896970147868,"score_gpt":0.2000631493335517,"score_spread":0.1960132523634038,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}