{"id":"W2951482915","doi":"10.1002/hon.99_2630","title":"EXPLORATORY BIOMARKER ANALYSIS IN THE PH 3 ECHELON‐1 STUDY: WORSE OUTCOME WITH ABVD IN PATIENTS WITH ELEVATED BASELINE LEVELS OF SCD30 AND TARC","year":2019,"lang":"en","type":"article","venue":"Hematological Oncology","topic":"Lymphoma Diagnosis and Treatment","field":"Medicine","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Spinal Cord Injury BC","funders":"","keywords":"Medicine; Brentuximab vedotin; Internal medicine; Dacarbazine; Oncology; ABVD; Biomarker; Post-hoc analysis; Progression-free survival; Gastroenterology; Lymphoma; Overall survival; CD30; Vincristine; Chemotherapy; Cyclophosphamide","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000639475,0.0001988175,0.001093166,0.0002869724,0.00001985225,0.000006831055,0.00009244357,0.0001402323,0.000160662],"category_scores_gemma":[0.0001027192,0.00008892624,0.00005602602,0.0009997287,0.0001324197,0.00006199215,0.00005027962,0.0001420716,0.00001079526],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001277141,"about_ca_system_score_gemma":0.0000831002,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007799021,"about_ca_topic_score_gemma":0.0006893628,"domain_scores_codex":[0.9981539,0.0004153932,0.0005108733,0.0003865802,0.0002805088,0.0002527763],"domain_scores_gemma":[0.9987097,0.0006098424,0.0001800811,0.0003302485,0.000100017,0.00007012374],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001583297,0.007455781,0.9883946,0.00003282452,0.0004289976,0.0005860046,0.0005203451,0.000007807586,0.00001695815,0.00007769692,0.00001230523,0.0008834283],"study_design_scores_gemma":[0.01398325,0.004207605,0.9798872,0.00004312096,0.0004885931,0.000019354,0.001067819,0.00007156718,0.00006507709,0.00001442316,0.00004486806,0.0001070598],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9978665,0.00008583989,0.00001236386,0.0005717242,0.00001470041,0.001249728,0.00001061989,0.00001332788,0.0001752364],"genre_scores_gemma":[0.9989738,0.000007750874,0.0003398148,0.0004926326,0.000003121462,0.0001345608,0.00002450703,0.000008392889,0.00001535307],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01239996,"threshold_uncertainty_score":0.3626307,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04577763203083163,"score_gpt":0.3204171451610274,"score_spread":0.2746395131301957,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}