{"id":"W2951497913","doi":"10.1128/jb.00794-18","title":"Ethanol Stimulates Trehalose Production through a SpoT-DksA-AlgU-Dependent Pathway in Pseudomonas aeruginosa","year":2019,"lang":"en","type":"article","venue":"Journal of Bacteriology","topic":"Bacterial biofilms and quorum sensing","field":"Biochemistry, Genetics and Molecular Biology","cited_by":26,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McGill University Health Centre","funders":"National Institute of Allergy and Infectious Diseases; National Center for Research Resources; National Institute of General Medical Sciences; National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; National Cancer Institute; National Institutes of Health; Government of Canada; Burroughs Wellcome Fund","keywords":"Trehalose; Sigma factor; Biology; Quorum sensing; Biofilm; Transcriptome; Pseudomonas aeruginosa; Biochemistry; Stringent response; Microbiology; Gene; Gene expression; Cell biology; Bacteria; Genetics; Mutant; Promoter","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001034093,0.0002579934,0.0002049551,0.0001248396,0.000142204,0.0002716183,0.0001238005,0.0001733247,0.0005638266],"category_scores_gemma":[0.0001781785,0.0001204046,0.0001721183,0.0001201152,0.0001285868,0.0002178095,0.000302219,0.0003803442,0.000284848],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002292071,"about_ca_system_score_gemma":0.0002058784,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002120132,"about_ca_topic_score_gemma":0.002291642,"domain_scores_codex":[0.9998655,0.00002625452,0.00001090044,0.00001657677,0.00004847952,0.00003230091],"domain_scores_gemma":[0.9999104,0.00002847375,0.00001250419,0.00001009904,0.00001679197,0.00002174545],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004613646,0.00002456323,0.0002135716,0.00001246656,0.000001090916,0.00003380009,0.00001496243,0.00003136216,0.9990609,0.0000251446,0.00001218537,0.0005238627],"study_design_scores_gemma":[0.000008205825,0.0002113924,0.01085627,0.000004425394,0.000005391719,0.0001373542,0.00008811423,0.001946582,0.986257,0.00006868294,0.0004076145,0.000008917785],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.998167,0.0002948043,0.0006823301,0.0001022669,0.000008350337,0.000009992302,0.0001167977,0.00002249664,0.0005959238],"genre_scores_gemma":[0.9978341,0.0001495356,0.0007500123,0.00002848788,0.000004181137,0.00001097501,0.0001424166,0.00000788492,0.001072453],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002120132,"threshold_uncertainty_score":0.004215598,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01125891796344249,"score_gpt":0.2418836212885659,"score_spread":0.2306247033251234,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}