{"id":"W2951541824","doi":"10.1080/19490976.2019.1629235","title":"Lipopolysaccharides modulate intestinal epithelial permeability and inflammation in a species-specific manner","year":2019,"lang":"en","type":"article","venue":"Gut Microbes","topic":"Inflammatory Bowel Disease","field":"Biochemistry, Genetics and Molecular Biology","cited_by":282,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary","funders":"Crohn's and Colitis Canada","keywords":"Biology; TLR4; Inflammatory bowel disease; Inflammation; Pathogenesis; Microbiome; Lipopolysaccharide; Intestinal permeability; Immunology; Microbiology; Disease; Bioinformatics; Medicine; Pathology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001562701,0.0002049098,0.0001396635,0.0001708334,0.00008203987,0.0002559693,0.00007566007,0.0002236809,0.0008919491],"category_scores_gemma":[0.000174517,0.00009746907,0.0002199857,0.00009411627,0.0001817353,0.0001847261,0.0002095448,0.0003782046,0.0001540072],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001090273,"about_ca_system_score_gemma":0.00009970816,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008750591,"about_ca_topic_score_gemma":0.0001472734,"domain_scores_codex":[0.9998535,0.00006041102,0.00001160987,0.00001624575,0.00001962458,0.00003856381],"domain_scores_gemma":[0.9998893,0.00001477672,0.00004188676,0.00001270937,0.00001617303,0.00002525669],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004580791,0.00007090379,0.001076396,0.00004627723,0.00001247356,0.00006651198,0.00002626785,0.00002950086,0.9964733,0.00004289257,0.00001788676,0.001679522],"study_design_scores_gemma":[0.0001139757,0.005397375,0.1227786,0.00004132027,0.0001131701,0.001003316,0.0003791325,0.0008321255,0.8664377,0.0003188158,0.002568185,0.00001634416],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9969759,0.001662615,0.0006620955,0.00009367533,0.0000262029,0.00001592475,0.00006007921,0.0000110165,0.0004925913],"genre_scores_gemma":[0.9983488,0.0007101724,0.0004416275,0.00006660261,0.000009853591,0.000009733231,0.00006375863,0.000002578063,0.0003468643],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008919491,"threshold_uncertainty_score":0.002983868,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006700603352654949,"score_gpt":0.207157953964298,"score_spread":0.200457350611643,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}