{"id":"W2951588326","doi":"10.1002/chin.200312181","title":"Design, Synthesis, and Neuraminidase Inhibitory Activity of GS‐4071 Analogues that Utilize a Novel Hydrophobic Paradigm.","year":2003,"lang":"en","type":"article","venue":"ChemInform","topic":"Aquaculture disease management and microbiota","field":"Immunology and Microbiology","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"","keywords":"Chemistry; Inhibitory postsynaptic potential; Neuraminidase; Combinatorial chemistry; Stereochemistry; Biochemistry; Neuroscience; Enzyme; Psychology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001776445,0.0004675745,0.0002750496,0.000157393,0.0002054043,0.0003329069,0.000444118,0.0003842415,0.002011941],"category_scores_gemma":[0.000154187,0.0002306963,0.0002643797,0.0001575807,0.000246432,0.000321359,0.0001995317,0.0006546779,0.0007871077],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004125275,"about_ca_system_score_gemma":0.000407811,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007050131,"about_ca_topic_score_gemma":0.001143906,"domain_scores_codex":[0.999925,0.00001413617,0.000006813547,0.00001139617,0.00001520306,0.0000273467],"domain_scores_gemma":[0.999951,0.000006604844,0.00001333203,0.000005330775,0.000007862244,0.00001589784],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008098196,0.0001990591,0.00005613172,0.0002580371,0.00002263292,0.0003224688,0.00005517012,0.001597572,0.9791976,0.00157298,0.0005277205,0.01538077],"study_design_scores_gemma":[0.0002878249,0.001691884,0.0002731019,0.00002000198,0.00003894726,0.000411113,0.00003683684,0.000998001,0.9774128,0.0002163459,0.01858748,0.00002577996],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9606285,0.007256323,0.0127076,0.0005849257,0.0002144365,0.0003994905,0.0007909252,0.0002006139,0.01721707],"genre_scores_gemma":[0.9780802,0.00502695,0.008389371,0.0002200162,0.00002874146,0.0001086405,0.0009644947,0.00003956816,0.00714213],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002011941,"threshold_uncertainty_score":0.006730676,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02649529549481252,"score_gpt":0.2251775791187374,"score_spread":0.1986822836239249,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}