{"id":"W2951608335","doi":"10.1097/01.hs9.0000558816.91319.ce","title":"S149 FIXED‐DURATION VENETOCLAX PLUS OBINUTUZUMAB IMPROVES PROGRESSION‐FREE SURVIVAL AND MINIMAL RESIDUAL DISEASE NEGATIVITY IN PATIENTS WITH PREVIOUSLY UNTREATED CLL AND COMORBIDITIES","year":2019,"lang":"en","type":"article","venue":"HemaSphere","topic":"Chronic Lymphocytic Leukemia Research","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen Elizabeth II Health Sciences Centre","funders":"","keywords":"Medicine; Internal medicine; Minimal residual disease; Gastroenterology; Venetoclax; Hazard ratio; Clinical endpoint; Obinutuzumab; Population; Surrogate endpoint; Progression-free survival; Oncology; Surgery; Confidence interval; Randomized controlled trial; Chronic lymphocytic leukemia; Bone marrow; Leukemia; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002004346,0.0002497147,0.0004223649,0.00005774517,0.00007284572,0.00006198079,0.00009667171,0.0001167365,0.0001147876],"category_scores_gemma":[0.0002430207,0.000184641,0.00002686503,0.0001791404,0.0002436449,0.0002422878,0.0001909012,0.0002251224,0.00001143048],"about_ca_system_candidate":true,"about_ca_system_consensus":true,"about_ca_system_score_codex":0.007338129,"about_ca_system_score_gemma":0.006947873,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009617296,"about_ca_topic_score_gemma":0.0006475411,"domain_scores_codex":[0.9980212,0.000123547,0.0002939812,0.0004945942,0.000640535,0.0004261184],"domain_scores_gemma":[0.9987732,0.0001974967,0.0001114708,0.0004926405,0.00013232,0.0002929207],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.02538037,0.000276931,0.9568065,0.004017008,0.0002061759,0.0004490401,0.002447592,0.0001101541,0.0005236345,0.0003555486,0.002012263,0.007414793],"study_design_scores_gemma":[0.07309794,0.002848598,0.9032204,0.001598435,0.000136456,0.00003304593,0.0008268856,0.01648046,0.0008571938,0.0001300245,0.0003008763,0.0004697413],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9964848,0.0007470135,0.000002013209,0.0001132455,0.00005340813,0.001885273,0.00004234277,0.00005195677,0.0006200093],"genre_scores_gemma":[0.9979722,0.00005109461,0.0003051864,0.00002976687,0.00006633217,0.00007662581,0.0001408628,0.00004020858,0.001317668],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.05358614,"threshold_uncertainty_score":0.9986818,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0093089771667384,"score_gpt":0.2535555672772715,"score_spread":0.2442465901105331,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}