{"id":"W2951621300","doi":"10.1002/chin.201205151","title":"ChemInform Abstract: Synthesis and Structure—Activity Relationship of 1‐ and 2‐Substituted 1,2,3‐Triazole Letrozole‐Based Analogues as Aromatase Inhibitors.","year":2012,"lang":"en","type":"article","venue":"ChemInform","topic":"Click Chemistry and Applications","field":"Chemistry","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Moncton","funders":"","keywords":"Chemistry; Letrozole; Aromatase; Triazole; 1,2,3-Triazole; Stereochemistry; Click chemistry; Combinatorial chemistry; Aromatase inhibitor; Organic chemistry; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001510626,0.0002754713,0.0003121308,0.0000577421,0.0001696164,0.00004014502,0.000150606,0.0003011699,0.0008572297],"category_scores_gemma":[0.0005520753,0.0002741179,0.00007785333,0.0001802436,0.0002784835,0.0004704212,0.00008310059,0.0002919028,0.000009797061],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006989366,"about_ca_system_score_gemma":0.00006789643,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005635867,"about_ca_topic_score_gemma":0.000004941326,"domain_scores_codex":[0.9987782,1.375881e-7,0.0004222308,0.0002334148,0.0002281662,0.0003378456],"domain_scores_gemma":[0.9983347,0.000517442,0.000344397,0.0004571307,0.0000581636,0.0002881789],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001466336,0.0002680418,0.01395464,0.001643911,0.0000997116,0.000002102732,0.0006595033,0.000001063875,0.8474624,0.0007411267,0.003006569,0.1320143],"study_design_scores_gemma":[0.0004333041,0.000003344125,0.009324013,0.00009565403,0.00008320841,0.00002665821,0.0002278522,0.00002180077,0.9840736,0.000113845,0.005310539,0.0002861957],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.8449684,0.0002030847,3.677702e-7,0.00007689563,0.00001784781,0.00008170164,0.0003667814,0.00006862331,0.1542163],"genre_scores_gemma":[0.9986228,0.00002370719,0.00006296188,0.00002237711,0.0001695349,0.00004823536,0.0003643659,0.00001878432,0.0006671783],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1536545,"threshold_uncertainty_score":0.9999711,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02402577297305244,"score_gpt":0.2616068645301119,"score_spread":0.2375810915570595,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}