{"id":"W2951621300","doi":"10.1002/chin.201205151","title":"ChemInform Abstract: Synthesis and Structure—Activity Relationship of 1‐ and 2‐Substituted 1,2,3‐Triazole Letrozole‐Based Analogues as Aromatase Inhibitors.","year":2012,"lang":"en","type":"article","venue":"ChemInform","topic":"Click Chemistry and Applications","field":"Chemistry","cited_by":1,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Moncton","funders":"","keywords":"Chemistry; Letrozole; Aromatase; Triazole; 1,2,3-Triazole; Stereochemistry; Click chemistry; Combinatorial chemistry; Aromatase inhibitor; Organic chemistry; Internal medicine","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001201361,0.0004876949,0.0002843504,0.0004673744,0.0001798389,0.0002359956,0.0002888104,0.0003323162,0.005743677],"category_scores_gemma":[0.0001170801,0.0002015559,0.0002146091,0.0003285542,0.0001277554,0.0002302493,0.0001350622,0.000338374,0.001166959],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003703381,"about_ca_system_score_gemma":0.0004345777,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001154194,"about_ca_topic_score_gemma":0.003327508,"domain_scores_codex":[0.9999409,0.000009920355,0.000004855543,0.000009780162,0.00001888757,0.00001572122],"domain_scores_gemma":[0.9999563,0.000006897183,0.00001243707,0.000004164493,0.000008034469,0.00001227981],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.001203177,0.0003263565,0.000488931,0.0005597384,0.00005104169,0.0003927062,0.0000458466,0.001297444,0.9599305,0.001162294,0.003316845,0.03122519],"study_design_scores_gemma":[0.0003798732,0.002615955,0.00364307,0.00002299123,0.0001154493,0.0007325345,0.00001544701,0.001206381,0.9713961,0.000118196,0.01972507,0.00002886156],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9042924,0.02558079,0.008918072,0.000763097,0.0003035017,0.0005751143,0.006012619,0.0007947295,0.05275957],"genre_scores_gemma":[0.9667273,0.009795028,0.004236665,0.0002874218,0.00005223578,0.0001053572,0.004116238,0.00002873907,0.01465108],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.005743677,"threshold_uncertainty_score":0.01921451,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02402577297305244,"score_gpt":0.2616068645301119,"score_spread":0.2375810915570595,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}