{"id":"W2951636677","doi":"10.1128/mbio.01226-18","title":"Candida albicans Hyphal Expansion Causes Phagosomal Membrane Damage and Luminal Alkalinization","year":2018,"lang":"en","type":"article","venue":"mBio","topic":"Antifungal resistance and susceptibility","field":"Medicine","cited_by":115,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Hospital for Sick Children","funders":"Canadian Institutes of Health Research","keywords":"Candida albicans; Microbiology; Hypha; Chemistry; Phagosome; Cell biology; Biology; Phagocytosis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001822658,0.0002133824,0.0001847273,0.0002130096,0.000205045,0.0005769303,0.0001962154,0.0003094663,0.0005640789],"category_scores_gemma":[0.0003046914,0.0001299027,0.000195168,0.0001685577,0.0003077891,0.0002704072,0.0004185315,0.0006532074,0.0001498044],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002793481,"about_ca_system_score_gemma":0.0002240307,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0009579472,"about_ca_topic_score_gemma":0.0008024536,"domain_scores_codex":[0.999692,0.00004425938,0.00001408503,0.00005844768,0.0001339607,0.00005735865],"domain_scores_gemma":[0.9997941,0.00003514222,0.00008001838,0.00002065293,0.00003740149,0.00003272755],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00006765089,0.00001704331,0.001394622,0.00004621333,0.000008226684,0.00006948686,0.00003172134,0.00008920793,0.9960069,0.0002629662,0.0001030426,0.001902955],"study_design_scores_gemma":[0.00001222959,0.0001854942,0.0689325,0.00002162869,0.00001856284,0.0007684053,0.0001669173,0.005263953,0.9206771,0.0005003663,0.003425174,0.00002763346],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9875429,0.002487988,0.006383733,0.0003622264,0.00005437878,0.00003216819,0.0003827281,0.0001313911,0.002622545],"genre_scores_gemma":[0.9969891,0.0006728895,0.001545849,0.0001225835,0.00001576121,0.00001661334,0.0001217988,0.00001110725,0.0005043867],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009579472,"threshold_uncertainty_score":0.002026856,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01576657268248485,"score_gpt":0.286052975309511,"score_spread":0.2702864026270261,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}