{"id":"W2951643410","doi":"10.1159/000500856","title":"AIHA and Pancytopenia as Complications of Pembrolizumab Therapy for Metastatic Melanoma: A Case Report","year":2019,"lang":"en","type":"article","venue":"Case Reports in Oncology","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Cancer Foundation; University of Alberta Hospital; Alberta Hospital Edmonton; University of Alberta","funders":"","keywords":"Pembrolizumab; Medicine; Pancytopenia; Ipilimumab; Nivolumab; Adverse effect; Prednisone; Internal medicine; Melanoma; Oncology; Immunosuppression; Anemia; Thrombocytopenic purpura; Immunotherapy; Immunology; Cancer; Immune system; Cancer research; Bone marrow","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0006519808,0.0001274631,0.0005500964,0.0001378625,0.00004333715,0.00000527555,0.00002102643,0.000099884,0.0001540544],"category_scores_gemma":[0.0001212083,0.0001067392,0.0001072873,0.0001326453,0.0001366513,0.00004285472,0.000020127,0.0001037507,0.000001577572],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001471721,"about_ca_system_score_gemma":0.0005361809,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00056512,"about_ca_topic_score_gemma":0.0002064261,"domain_scores_codex":[0.9985453,0.0000557108,0.0007888496,0.0003450899,0.00008497955,0.0001800464],"domain_scores_gemma":[0.9985265,0.0002808047,0.0004751048,0.0005104716,0.0001366785,0.00007048091],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.002711272,0.0004702203,0.007608337,0.0001704245,0.0002587422,0.9341412,0.0006235109,0.000001719293,0.009067019,0.0002094094,0.0004294878,0.04430863],"study_design_scores_gemma":[0.004937593,0.001597301,0.003388835,0.00003990023,0.00008480246,0.9246216,0.0003873539,0.00004206203,0.001345947,0.0002802994,0.06317416,0.0001001645],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9907714,0.002471521,0.00007492803,0.0009277078,0.000236093,0.001767498,0.00001187129,0.00001695237,0.003722084],"genre_scores_gemma":[0.9966767,0.0002267287,0.001489827,0.0005131662,0.00002566262,0.0002543763,0.00003112308,0.00001971378,0.0007626837],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06274467,"threshold_uncertainty_score":0.4352697,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03628936030286715,"score_gpt":0.3719240120610183,"score_spread":0.3356346517581511,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}