{"id":"W2951643410","doi":"10.1159/000500856","title":"AIHA and Pancytopenia as Complications of Pembrolizumab Therapy for Metastatic Melanoma: A Case Report","year":2019,"lang":"en","type":"article","venue":"Case Reports in Oncology","topic":"Cancer Immunotherapy and Biomarkers","field":"Medicine","cited_by":24,"is_retracted":false,"has_abstract":true,"ca_institutions":"Alberta Cancer Foundation; University of Alberta Hospital; Alberta Hospital Edmonton; University of Alberta","funders":"","keywords":"Pembrolizumab; Medicine; Pancytopenia; Ipilimumab; Nivolumab; Adverse effect; Prednisone; Internal medicine; Melanoma; Oncology; Immunosuppression; Anemia; Thrombocytopenic purpura; Immunotherapy; Immunology; Cancer; Immune system; Cancer research; Bone marrow","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005180681,0.002803489,0.001906292,0.003937576,0.004245937,0.002310093,0.001644191,0.006970813,0.002603861],"category_scores_gemma":[0.002499613,0.001815529,0.002122636,0.002770547,0.001918621,0.003751755,0.00249545,0.005668422,0.001025039],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001852567,"about_ca_system_score_gemma":0.00129131,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003226969,"about_ca_topic_score_gemma":0.00449652,"domain_scores_codex":[0.9987626,0.0001629525,0.0001576115,0.0002999219,0.0001982251,0.0004187139],"domain_scores_gemma":[0.9985654,0.0003032753,0.0003829914,0.0001246763,0.0001012488,0.0005224389],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"case_report","study_design_gemma":"case_report","study_design_scores_codex":[0.00001390237,0.00003255114,0.002225963,0.00003256086,0.00001283593,0.9958693,0.0001211542,0.00003862592,0.000278938,0.0001116395,0.0003308884,0.0009314708],"study_design_scores_gemma":[0.000005685907,0.00002076904,0.0009220371,0.00001290881,0.00001167947,0.9983082,0.00005665168,0.00008976768,0.00009844272,0.00007743168,0.0003900238,0.000006405408],"study_design_candidate":"case_report","study_design_consensus":"case_report","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9058444,0.05218663,0.0099671,0.008958075,0.00146498,0.0006412313,0.000498216,0.0005196498,0.01991981],"genre_scores_gemma":[0.9820606,0.00856331,0.002422522,0.002175571,0.002226903,0.00008080697,0.0001763652,0.00005082555,0.002243201],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006970813,"threshold_uncertainty_score":0.01344138,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03628936030286715,"score_gpt":0.3719240120610183,"score_spread":0.3356346517581511,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}