{"id":"W2951653534","doi":"10.1002/chin.200622187","title":"Liphagal, a Selective Inhibitor of PI3 Kinase α Isolated from the Sponge Aka coralliphaga: Structure Elucidation and Biomimetic Synthesis.","year":2006,"lang":"en","type":"article","venue":"ChemInform","topic":"Synthesis and biological activity","field":"Chemistry","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Chemistry; AKA; Sponge; Combinatorial chemistry; Nanotechnology; Stereochemistry; Computational biology; Botany; Library science; Computer science","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001107229,0.0006043619,0.0002729924,0.0005704038,0.0001651213,0.0002702235,0.0003612083,0.0002478366,0.002147829],"category_scores_gemma":[0.0001015006,0.0002059402,0.0003396533,0.000316978,0.0002435961,0.0003074322,0.0002988657,0.0006571239,0.001114833],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002725431,"about_ca_system_score_gemma":0.0003288111,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005446554,"about_ca_topic_score_gemma":0.001026467,"domain_scores_codex":[0.9999459,0.000006537001,0.000004806706,0.00001092869,0.00001542893,0.00001654937],"domain_scores_gemma":[0.9999675,0.000004650552,0.000007156479,0.000004786732,0.000004024702,0.00001194418],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000212872,0.00004057738,0.00006776043,0.0002802906,0.00001689202,0.0001729243,0.00001154404,0.0002245376,0.9870405,0.0002103522,0.0002501828,0.01147156],"study_design_scores_gemma":[0.000217545,0.001135126,0.001416902,0.00002818662,0.00008324107,0.0006417033,0.00002225772,0.0003676546,0.9794232,0.0001728276,0.01647193,0.00001940733],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.830191,0.06677757,0.04561578,0.001482734,0.0005369004,0.001759408,0.01023364,0.001675551,0.04172737],"genre_scores_gemma":[0.9320607,0.02726686,0.016731,0.0004138923,0.00005439093,0.0002978847,0.007897115,0.0001232997,0.01515481],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002147829,"threshold_uncertainty_score":0.007185161,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007826938649850011,"score_gpt":0.1975991339217732,"score_spread":0.1897721952719232,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}