{"id":"W2951688625","doi":"10.1016/j.kint.2019.05.032","title":"The caveolin-1 regulated protein follistatin protects against diabetic kidney disease","year":2019,"lang":"en","type":"article","venue":"Kidney International","topic":"Caveolin-1 and cellular processes","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":false,"ca_institutions":"McMaster University","funders":"Canadian Institutes of Health Research","keywords":"Follistatin; Internal medicine; Endocrinology; Podocyte; Caveolin 1; Diabetic nephropathy; Downregulation and upregulation; Nephrin; Glomerular basement membrane; Caveolae; Kidney; Glomerulosclerosis; Biology; Medicine; Glomerulonephritis; Cell biology; Signal transduction; Proteinuria","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002410429,0.0003679446,0.0005458398,0.0002999599,0.0002244444,0.0004737376,0.0003358054,0.0003969618,0.001416835],"category_scores_gemma":[0.0001691922,0.0001546689,0.0003000431,0.0001736584,0.0002324336,0.0003119177,0.0002183967,0.0009676422,0.0002180994],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002641892,"about_ca_system_score_gemma":0.0003323583,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00078311,"about_ca_topic_score_gemma":0.0009823168,"domain_scores_codex":[0.9998984,0.00001575748,0.000009351928,0.00001700471,0.00001899882,0.00004057325],"domain_scores_gemma":[0.9998466,0.000008442703,0.00003736277,0.00001734777,0.00001596763,0.00007433529],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.02161659,0.001261288,0.002128617,0.0002009837,0.00023373,0.0001297244,0.00003795389,0.0002046454,0.953564,0.0003850482,0.000540216,0.01969711],"study_design_scores_gemma":[0.002253114,0.008952361,0.0561909,0.00006648414,0.0007954595,0.0005027711,0.00015846,0.001993566,0.9212831,0.0007131705,0.007045513,0.00004508468],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928049,0.004673402,0.0007472755,0.0003042105,0.0001541126,0.00001232176,0.0001425217,0.0001186259,0.001042673],"genre_scores_gemma":[0.9946295,0.001575227,0.0006399797,0.0001570628,0.00004365059,0.00001147551,0.0002461407,0.00001502975,0.002681875],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001416835,"threshold_uncertainty_score":0.004739761,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.003775197596336209,"score_gpt":0.2129001136704695,"score_spread":0.2091249160741333,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}