{"id":"W2951788119","doi":"10.1021/ol8024605","title":"Silver Ion-Induced Grob Fragmentation of γ-Amino Iodides: Highly Stereoselective Synthesis of Polysubstituted Piperidines","year":2008,"lang":"en","type":"article","venue":"Organic Letters","topic":"Synthetic Organic Chemistry Methods","field":"Chemistry","cited_by":30,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université de Montréal","funders":"","keywords":"Chemistry; Stereoselectivity; Fragmentation (computing); Indolizidine; Reagent; Ion; Grignard reagent; Stereochemistry; In situ; Combinatorial chemistry; Organic chemistry; Catalysis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002040095,0.0005808843,0.0003037421,0.0002222686,0.0001484582,0.000204832,0.000385502,0.0002483224,0.0009347805],"category_scores_gemma":[0.0001842884,0.0002289699,0.0001879685,0.0001559699,0.0002604011,0.0002696745,0.0002321251,0.0006348221,0.0005240978],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003229503,"about_ca_system_score_gemma":0.0002748506,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003737564,"about_ca_topic_score_gemma":0.001260451,"domain_scores_codex":[0.999872,0.00001514726,0.00001057568,0.00003564982,0.00003364951,0.0000329542],"domain_scores_gemma":[0.9998686,0.00001254462,0.0000475888,0.0000168862,0.00001972541,0.00003474486],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004139664,0.000009242734,0.000028731,0.0000435276,0.000002852848,0.0001029477,0.00002951431,0.0001068139,0.9978947,0.0001433024,0.00003390706,0.001563074],"study_design_scores_gemma":[0.00002035483,0.0002179175,0.0002776484,0.000003337419,0.000005390337,0.0001874287,0.000008982965,0.0003307653,0.9972331,0.00002962933,0.00167765,0.000007863955],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9689108,0.00228881,0.02267388,0.0001405126,0.00006519702,0.0001311122,0.0004932402,0.0004118178,0.004884636],"genre_scores_gemma":[0.9692007,0.001349893,0.02546754,0.00007300492,0.00002028956,0.00005864466,0.0004078483,0.00008577147,0.003336307],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009347805,"threshold_uncertainty_score":0.003127158,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01919473549434436,"score_gpt":0.241624447184722,"score_spread":0.2224297116903776,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}