{"id":"W2951830857","doi":"10.4049/jimmunol.1900033","title":"SIMON, an Automated Machine Learning System, Reveals Immune Signatures of Influenza Vaccine Responses","year":2019,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"Influenza Virus Research Studies","field":"Medicine","cited_by":64,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute of Infection and Immunity","funders":"National Institute of Allergy and Infectious Diseases","keywords":"Immune system; Influenza vaccine; Virology; Immunology; Medicine; Computer science; Artificial intelligence; Vaccination","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00343074,0.0002149785,0.001017247,0.0004940875,0.0001483812,0.00001041347,0.0004971286,0.0001755819,0.0001477319],"category_scores_gemma":[0.00202282,0.0001234563,0.0001630929,0.0003561242,0.0001766126,0.0001717651,0.0002060885,0.001271688,0.00005825127],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001384184,"about_ca_system_score_gemma":0.0001951233,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001676371,"about_ca_topic_score_gemma":0.000005031268,"domain_scores_codex":[0.9963502,0.001509634,0.001157019,0.0001237921,0.0004643633,0.0003949883],"domain_scores_gemma":[0.9962352,0.001039458,0.001083648,0.0005409236,0.00103328,0.00006749643],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.0192247,0.0001302508,0.02577262,0.0002546158,0.001352,0.00007320647,0.001305922,0.0009569329,0.9499493,0.000134567,0.0002391568,0.0006067813],"study_design_scores_gemma":[0.0157583,0.01868169,0.8174462,0.002293622,0.0008346055,0.002419078,0.008423876,0.003361632,0.1210621,0.0000900151,0.009194347,0.000434596],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9561319,0.04243724,0.000008158054,0.0004459523,0.0002071996,0.000353983,0.000006905331,0.00008749916,0.0003211578],"genre_scores_gemma":[0.9979833,0.001005877,0.000178234,0.0001975394,0.00007835117,0.000002348347,0.000002515869,0.00003365786,0.0005181863],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8288872,"threshold_uncertainty_score":0.5524923,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03246845623624576,"score_gpt":0.362638959504516,"score_spread":0.3301705032682702,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}