{"id":"W2951888728","doi":"10.1021/acs.biomac.9b00417","title":"Cross-Linked Elastin-like Polypeptide Membranes as a Model for Medial Arterial Calcification","year":2019,"lang":"en","type":"article","venue":"Biomacromolecules","topic":"Connective tissue disorders research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":29,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Université de Montréal; Hospital for Sick Children; McGill University","funders":"Natural Sciences and Engineering Research Council of Canada; Canadian Institutes of Health Research; Polytechnique Montréal; Heart and Stroke Foundation of Canada; Fonds Québécois de la Recherche sur la Nature et les Technologies; Canadian Light Source; Canada Research Chairs","keywords":"Elastin; Calcification; Calcium; Chemistry; Mineralization (soil science); Nucleation; Membrane; Biophysics; In vivo; Anatomy; Biochemistry; Internal medicine; Pathology; Biology; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001759226,0.0002151943,0.0001852562,0.00007852729,0.0001076257,0.00008091574,0.0003252662,0.0002176877,0.00009771115],"category_scores_gemma":[0.0002265382,0.0002187155,0.0001541699,0.00009997544,0.0001419155,0.000008007041,0.0001235197,0.0000588265,0.0001576772],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000218432,"about_ca_system_score_gemma":0.0001855993,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005053943,"about_ca_topic_score_gemma":0.00006391142,"domain_scores_codex":[0.9984587,0.00005130824,0.0002408721,0.0006083116,0.0002272504,0.0004134872],"domain_scores_gemma":[0.999079,0.00003640694,0.00008273921,0.0004539456,0.0002335579,0.0001142954],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008302918,0.00007847897,0.0004020557,0.00005261663,0.00005256691,0.000002126562,0.00008938362,0.0001419735,0.9965507,0.0002827105,0.0004038342,0.001113252],"study_design_scores_gemma":[0.003596245,0.0005607005,0.002382271,0.00001774942,0.00002388952,0.00002529334,0.00008163851,0.01824229,0.9600146,0.000725086,0.01379047,0.0005397071],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9880713,0.0003926498,0.009418583,0.0001772461,0.0003316504,0.0008352391,0.0001272494,0.00003276832,0.0006133355],"genre_scores_gemma":[0.9936721,0.00003227096,0.0008406166,0.0001215915,0.0002550411,0.0001757047,0.0006440409,0.00005414845,0.00420449],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03653605,"threshold_uncertainty_score":0.8918959,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02047108008570029,"score_gpt":0.3270097717020986,"score_spread":0.3065386916163982,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}