{"id":"W2951914067","doi":"10.1021/acs.orglett.9b01893","title":"Iodine(III)-Mediated Contraction of 3,4-Dihydropyranones: Access to Polysubstituted γ-Butyrolactones","year":2019,"lang":"en","type":"article","venue":"Organic Letters","topic":"Oxidative Organic Chemistry Reactions","field":"Chemistry","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre in Green Chemistry and Catalysis; Université de Sherbrooke","funders":"Fonds de recherche du Québec – Nature et technologies; Natural Sciences and Engineering Research Council of Canada; Canada Foundation for Innovation; Université de Sherbrooke","keywords":"Chemistry; Stereocenter; Steric effects; Iodine; Combinatorial chemistry; Reagent; Stereochemistry; Organic chemistry; Catalysis; Enantioselective synthesis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.00009924769,0.0003099936,0.0004508689,0.0001140253,0.00008335392,0.00006893928,0.0005511331,0.0001805161,0.01423811],"category_scores_gemma":[0.0002012868,0.0003208654,0.0001157966,0.0005947593,0.00007343381,0.0003300911,0.0001466349,0.000335376,0.0009491005],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003123601,"about_ca_system_score_gemma":0.0001257556,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002593882,"about_ca_topic_score_gemma":0.00004262163,"domain_scores_codex":[0.9981686,0.00001708307,0.0004799155,0.0005099633,0.0003791385,0.0004452718],"domain_scores_gemma":[0.9984713,0.0002082164,0.0002924821,0.0007056431,0.0001298112,0.0001926109],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001098319,0.0001078559,0.004914379,0.0001031393,0.0001395512,0.000008026785,0.0003346086,0.00004060505,0.9925467,0.000005893116,0.001601256,0.00008813935],"study_design_scores_gemma":[0.001500163,0.00001261759,0.001042023,0.00006664987,0.00006714035,0.00002865153,0.0003390787,0.0001246224,0.994063,0.000003207036,0.002405468,0.0003474258],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9932319,0.00002319287,0.0004396435,0.003271206,0.000336259,0.0002202554,0.00006865265,0.000216878,0.002192026],"genre_scores_gemma":[0.9980451,0.000009769304,0.00007833325,0.0009420471,0.0001981827,0.00001769427,0.0001234483,0.00006883166,0.0005166252],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.013289,"threshold_uncertainty_score":0.9999244,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01055383811688142,"score_gpt":0.2413775732243381,"score_spread":0.2308237351074566,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}