{"id":"W2951914067","doi":"10.1021/acs.orglett.9b01893","title":"Iodine(III)-Mediated Contraction of 3,4-Dihydropyranones: Access to Polysubstituted γ-Butyrolactones","year":2019,"lang":"en","type":"article","venue":"Organic Letters","topic":"Oxidative Organic Chemistry Reactions","field":"Chemistry","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"Centre in Green Chemistry and Catalysis; Université de Sherbrooke","funders":"Fonds de recherche du Québec – Nature et technologies; Natural Sciences and Engineering Research Council of Canada; Canada Foundation for Innovation; Université de Sherbrooke","keywords":"Chemistry; Stereocenter; Steric effects; Iodine; Combinatorial chemistry; Reagent; Stereochemistry; Organic chemistry; Catalysis; Enantioselective synthesis","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002251762,0.0006925281,0.0002247624,0.0002566634,0.0001421048,0.0002171486,0.0004183968,0.0002807025,0.001853772],"category_scores_gemma":[0.0002162973,0.0001391117,0.0002274331,0.0002376385,0.0002953463,0.0003891536,0.0004202161,0.0005996321,0.0005551624],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002938173,"about_ca_system_score_gemma":0.0002952846,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005455644,"about_ca_topic_score_gemma":0.001407701,"domain_scores_codex":[0.9998493,0.0000197399,0.00001079639,0.00002681277,0.00002214805,0.00007105838],"domain_scores_gemma":[0.9999161,0.00001678873,0.00002363469,0.00001204036,0.000009431557,0.00002211753],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001640142,0.00007129572,0.0002017245,0.0002518089,0.00002041494,0.0006449735,0.0002384831,0.001067537,0.9858084,0.001525941,0.0003723051,0.009633118],"study_design_scores_gemma":[0.00002657023,0.0005195739,0.0006875415,0.00002092059,0.00001621432,0.0002942337,0.00004686117,0.0006565994,0.9910111,0.0002053604,0.006494661,0.00002035117],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9587244,0.005509824,0.01463765,0.0003375669,0.0001357854,0.000146253,0.0007161566,0.0002222084,0.01957017],"genre_scores_gemma":[0.9910821,0.002693195,0.003402204,0.00007748348,0.00001618187,0.00002462752,0.0002035073,0.00003122944,0.002469439],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001853772,"threshold_uncertainty_score":0.006201446,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01055383811688142,"score_gpt":0.2413775732243381,"score_spread":0.2308237351074566,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}